An Implantable Antenna Made of Silk Alerts Doctors of Disease
Saturday, August 21st, 2010Silk and gold, usually a pairing for the runways of Milan, are now the main ingredients for a new kind of implantable biosensor. Researchers at Tufts University have crafted a small antenna from liquid silk and micropatterned gold. The antenna is designed to spot specific proteins and chemicals in the body, and alert doctors wirelessly to signs of disease. Scientists say the implant could someday help patients with diabetes track their glucose levels without having to test themselves daily.
Silky sensor: A biosensor made from silk and gold can pick up tiny signals from proteins and chemicals in the body. Researchers patterned gold over a silk film and wrapped it into a capsule shape to form a small antenna.
According to Fiorenzo Omenetto, professor of biomedical engineering at Tufts University, silk is a natural platform for medical implants–it’s biocompatible, and while it’s delicate and pliable, it’s also tougher than Kevlar. Implanted in the body, silk can conform to any tissue surface, and, unlike conventional polymer-based implants, it could stay in place over a long period of time without adverse effects. Omenetto has previously taken advantage of these properties to mold silk into tiny chips and flexible meshes, pairing the material with transistors to track molecules, and with electrodes to monitor brain activity.
Now Omenetto is exploring the combination of silk and metamaterials–metals like gold, copper, and silver manipulated at the micro- and nanoscale to exhibit electromagnetic characteristics not normally found in nature. For example, scientists have created metamaterials that act as “invisibility cloaks” by manipulating metals to bend light all the way around an object, rendering it invisible.
Omenetto and his colleague Richard Averitt, associate professor of physics at Boston University, used similar principles to create a metamaterial that’s responsive not to visible light, but rather to frequencies further down the electromagnetic spectrum, within the terahertz range. Not coincidentally, proteins, enzymes, and chemicals in the body are naturally resonant at terahertz frequencies, and, according to Averitt, each biological agent has its own terahertz “signature.”
Terahertz science is a new and growing field, and several research groups are investigating specific protein “T-ray” signatures. A silk metamaterial antenna could someday pick up these specific signals and then send a wireless signal to a computer, to report on chemical levels and monitor disease.
To engineer the responsive end of such an antenna, the team first created a biocompatible base by boiling down silk and pouring the liquid solution into a centimeter-square film. The researchers then sprayed gold onto the silk film, using tiny stencils to create different patterns all along the film. Each area of the film responds to a different terahertz frequency depending on the shape of the gold pattern. The team then wrapped the patterned film around a capsule to form an antenna.
To test its performance, Omenetto and Averitt subjected the antenna to terahertz radiation and found that the antenna was resonant at specific frequencies. Going a step further, the researchers implanted the antenna in several layers of muscle tissue from a pig, and still detected a terahertz signal.
“We’ll try to sense something next and maybe put the antenna in contact with something we’d like to detect, like glucose,” says Omenetto. “We’ll see if we can replicate a proof of principle, and try to add some meaning to the resonance.”
Rajesh Naik, a materials science expert at the Air Force Research Laboratory at Wright-Patterson Air Force Base, says the research has great practical potential.
“Proteins and other molecules can be entrapped within silk films, allowing one to monitor in-vivo chemical reactions,” says Naik. “Similar resonating structures can be patterned onto other polymeric materials, but silk has an added advantage of being biocompatible.”
Miracle of Magnetics
Tuesday, August 17th, 2010The human body floats in a sea of magnetic fields – those of the earth, moon, sun, and other galactic fields. The body is full of magnetic materials. Every cell and atom of the body is a small magnetic dynamo. The body’s fields, which are very tiny, are measured in devices called SQUIDS. The earth’s field is 100,000 times or more stronger than the body’s! We are so dependent on the earth’s fields that astronauts in space for long periods require artificial magnetic fields to maintain health.
Magnetic fields penetrate the body as if it were air. Nothing in the body stands in the way of a magnetic field. The body is 70% or more water, which doesn’t reduce or block magnetic fields. A strong magnet held on one side of the hand can easily deflect a compass needle on the other side of the same hand.
SQUIDS show that tissues exposed to magnets have enhanced magnetic signals afterward for some time. Various types of magnets produce these effects. They include permanent magnets, such as flat magnetic pads and electromagnets of various kinds, such as MRI machines and nerve conduction testing devices.
Some acupuncturists use permanent magnets because they are painless and allow treatment to continue after a visit. While a student in acupuncture, I was experimenting on myself with two of the most powerful acupuncture magnets available. In two separate trials, I felt an obvious buzzing sensation in my chest and abdomen. By chance I stimulated two acupuncture meridians! This proved that magnets significantly affect acupuncture points and meridians. I also worked with a physician friend who owns some sensitive electrical testing equipment. We were able to show that magnets increase the energy (chi) flow along a hand meridian. In my practice, I now frequently replace needles for magnets.
Magnetics act on the body in many ways:
I hope the above has helped to inform you about the exciting new field of biomagnetics which has great potential to help people. We are clearly seeing a new day in medical sciences and health care with the expanded awareness and use of complementary techniques of care.
They stimulate the acupuncture points and meridians. In this way, they can be used for all kinds of problems, especially for pain, fibromyalgia and muscle strains.
They work on red blood cells because they contain iron. I placed a round bullseye magnet on a nurse’s knee bruise following a ski injury. The next morning she had a perfect bullseye pattern over her bruise!
Most people report warmth and gentle tingling under the magnets. Europeans have measured increased blood flow. Others have seen this on thermograms too.
They affect some chemical processes within and between cells. Chemists use sensitive magnetic equipment to measure simple and complex molecules. Researchers at Harvard found that salt water passes a membrane quicker with a magnetic field.
They can affect nerve signals. High strength magnets can cause anesthesia, through a principle in physics called the Hall effect. Dr. Robert Becker (author of Body Electric) put salamanders to sleep before surgery with electromagnets more safely than anesthetics. Magnets can stop epileptic seizures. They are also used to study and map nerve structures deep in the brain, normally only accessible during brain surgery.
Introducing – L-Carnosine
Tuesday, August 17th, 2010L-Carnosine is a dipeptide consisting of of ß-alanine linked at its carboxyl terminus to the amino group of L-histidine (ß-alanyl-L-histidine). It is synthesized by the enzyme carnosine synthetase, and broken down by carnosinase. It is widely distributed in tissues, and is present at particularly high concentrations in skeletal muscle and the olfactory lobe of the brain. Carnosine has a number of important properties, including antioxidant activity, ability to chelate divalent cations such as copper, neutralization of acids (such as lactic acid), and the inhibition of nonenzymic glycosylation of proteins. It is found in long-lived tissues in surprisingly high amounts (up to 20 mM in human muscle) and has been shown to delay aging in cultured cells. When added to cultures of human lung and foreskin fibroblasts, the dipeptide extended cell survival and increased maximal cell division potential while also inducing a more juvenile phenotype in senescent human and rodent cells. This suggests that other properties of the dipeptide are involved. There are suggestions that the concentration of tissue-associated L-carnosine declines with age. L-Carnosine and related dipeptides have been shown to prevent peroxidation of model membrane systems, suggesting that they represent water-soluble counterparts to lipid-soluble antioxidants such as a-tocopherol in protecting cell membranes from oxidative damage. Other roles ascribed to this dipeptide include acting as a neurotransmitter in the modulation of enzyme activities.
L-Carnosine significantly reduces the formation of 8-hydroxy deoxyguanosine (8-OH dG) in cultured cells, thus demonstrating protection of DNA. The presumptive anti-senescent effect of L-carnosine may be related to this inhibition. L-Carnosine also inhibits protein carbonyl formation. A common molecular indication of cellular aging is the accumulation of aberrant proteins, especially polypeptides bearing carbonyl (CO) groups.
Introducing – Aceytl-L-Carnitine
Tuesday, August 17th, 2010Acetyl-L-carnitine (ALC) is an ester of the trimethylated amino acid, L-carnitine, and is synthesized in the brain, liver and kidney by a specific enzyme carnitine acetyltransferase, which declines with age in animals. ALC facilitates the uptake of acetyl-groups into the mitochondria during fatty acid oxidation, enhances acetylcholine production and stimulates protein and membrane phospholipid synthesis. ALC is actively transported across the blood-brain barrier. It influences the cholinergic system as a cholinergic receptor agonist (facilitator) and may also promote synthesis and release of acetylcholine. More generally, ALC participates in cellular energy production and in maintenance and repair processes in neurons.
ALC aids in the transport of substances across the membrane of mitochondria, thereby participating in the production of energy within the brain. ALC reverses the age-related decline in the number of N-methyl-D-aspartic acid (NMDA) receptors on the neuron membrane. ALC elevates the levels of neurotrophins such as nerve growth factor (NGF). The neurotrophins are a family of structurally related proteins that function during development to guide the differentiation and growth of neurons. They also participate in the maintenance of adult neurons and are important in the repair of damage.
ALC reduces deficits in brain energy metabolism and phospholipid metabolism in rats by aiding mitochondrial function. ALC improves nerve regeneration in rats and protects neurons from the toxicity of mitochondrial uncouplers or inhibitors. Feeding senescent rats with ALC restores levels of this metabolite to those found in tissues of young rats. Treatment of these rats with ALC restores cardiolipin in mitochondrial membranes to levels which are found in younger rats. Cardiolipin (diphosphatidylglycerol) is a phospholipid which is biosynthesized and concentrated almost exclusively in the inner mitochondrial membrane. It is the only cardiolipid whose levels are found to be reduced in the mitochondria of older rats. Maximal activity of cytochrome c oxidase, necessary for cellular energetics, appears to depend upon cardiolipin levels. Clinical trials with ALC showed some improvements in cognitive function and improvement in memory, visuospatial capacity, vocabulary recall, cooperation, sociability and attention.
Acetyl-L-carnitine (ALC) is an ester of the trimethylated amino acid, L-carnitine, and is synthesized in the brain, liver and kidney by a specific enzyme carnitine acetyltransferase, which declines with age in animals. ALC facilitates the uptake of acetyl-groups into the mitochondria during fatty acid oxidation, enhances acetylcholine production and stimulates protein and membrane phospholipid synthesis. ALC is actively transported across the blood-brain barrier. It influences the cholinergic system as a cholinergic receptor agonist (facilitator) and may also promote synthesis and release of acetylcholine. More generally, ALC participates in cellular energy production and in maintenance and repair processes in neurons.
ALC aids in the transport of substances across the membrane of mitochondria, thereby participating in the production of energy within the brain. ALC reverses the age-related decline in the number of N-methyl-D-aspartic acid (NMDA) receptors on the neuron membrane. ALC elevates the levels of neurotrophins such as nerve growth factor (NGF). The neurotrophins are a family of structurally related proteins that function during development to guide the differentiation and growth of neurons. They also participate in the maintenance of adult neurons and are important in the repair of damage.ALC reduces deficits in brain energy metabolism and phospholipid metabolism in rats by aiding mitochondrial function. ALC improves nerve regeneration in rats and protects neurons from the toxicity of mitochondrial uncouplers or inhibitors. Feeding senescent rats with ALC restores levels of this metabolite to those found in tissues of young rats. Treatment of these rats with ALC restores cardiolipin in mitochondrial membranes to levels which are found in younger rats. Cardiolipin (diphosphatidylglycerol) is a phospholipid which is biosynthesized and concentrated almost exclusively in the inner mitochondrial membrane. It is the only cardiolipid whose levels are found to be reduced in the mitochondria of older rats. Maximal activity of cytochrome c oxidase, necessary for cellular energetics, appears to depend upon cardiolipin levels. Clinical trials with ALC showed some improvements in cognitive function and improvement in memory, visuospatial capacity, vocabulary recall, cooperation, sociability and attention.
Weight Gain In Adulthood Linked to Prostate Cancer Risk
Friday, August 13th, 2010Body size and weight gain in younger and older adulthood may help weigh a man’s proneness to prostate cancer, according to a study by researchers at the University of Hawaii at Manoa’s Cancer Research Center of Hawaii.
Led by Dr. Brenda Hernandez, the researchers said that the risk varies among different ethnic groups
For the study, the researchers studied the relationship in a multiethnic population consisting of blacks, Japanese, Hispanics, Native Hawaiians and whites, and compared differences among age groups using the Multiethnic Cohort, a longitudinal study of men 45-75 years of age established in Hawaii and California from 1993-1996.
Of the 83,879 men who participated in the study, 5,554 developed prostate cancer.
Overall, men who were overweight or obese by age 21 had a decreased risk of localized and low-grade prostate cancer, according to Hernandez.
Their results suggested that being overweight in older adulthood was associated with increased prostate cancer risk among white and Native Hawaiian men, but a decreased risk among Japanese men.
While excessive weight gain between younger and older adulthood was observed to increase the risk of advanced and high-grade prostate cancers in white men and increase the risk of localized and low-grade disease in black men, it appeared to decrease the risk of localized prostate cancer in Japanese men.
“The relationship of certain characteristics, such as body size, with cancer risk may vary across ethnic groups due to the combined influence of both genes and lifestyle,” said Hernandez.
However, the relationship between body size and prostate cancer risk is not entirely understood.
Excess fat is associated with a number of conditions that contribute to cancer development including low-grade chronic inflammation, insulin resistance, metabolic abnormalities, and hormone imbalances.
These conditions may in turn contribute to more aggressive prostate malignancies.
Ethnic differences in cancer risk may be explained by differences in the distribution of stored body fat that could have a differential effect on the development of prostate cancer.
And the distribution of body fat may influence the specific way that excess fat influences cancer risk.
Eye Disease Affects Nearly One in Three Diabetics
Friday, August 13th, 2010Almost one in three people with diabetes has evidence of the eye disease called diabetic retinopathy, according to new research.
What’s more, over 4 percent of people with diabetes have diabetic retinopathy that’s so advanced it’s threatening their vision, reports the study published in the Aug. 11 issue of the Journal of the American Medical Association.
”This was a national population-based study and we found that among Americans with diabetes who were age 40 and older, that 28.5 percent — or 4.2 million people — have diabetic retinopathy. And, 4.4 percent had vision-threatening diabetic retinopathy,” said the study’s lead author, Dr. Xinzhi Zhang, an epidemiologist with the U.S. Centers for Disease Control and Prevention in Atlanta.
The news wasn’t all bad, however. The findings suggest that good control of blood sugar, blood pressure and cholesterol can go a long way toward preventing or slowing diabetic eye disease. And treatment with laser surgery may be helpful for those with more advanced retinopathy.
”If you have diabetes, take good care of your diabetes and get your eyes examined regularly,” advised Zhang. “If you find problems early and get treatment, you can delay or prevent the loss of vision.”
Diabetic retinopathy causes changes in the blood vessels in the eyes. In some cases, new and abnormal blood vessels grow, and in other cases, existing blood vessels swell and leak, according to the U.S. National Eye Institute. Diabetic retinopathy remains the number one cause of vision loss in people aged 20 to 74 in the United States, according to background information in the study.
The last study that looked at national prevalence of diabetic retinopathy was done between 1988 and 1994. To get an updated estimate of what the prevalence of the eye disease might be now, Zhang and his colleagues reviewed data from the National Health and Nutrition Examination Survey from 2005 to 2008, which included nearly 7,000 people over age 40.
Of those people, 1,006 reported that they had been diagnosed with diabetes, or they had a hemoglobin A1C reading above 6.5 percent. Hemoglobin A1C is a measure of long-term blood sugar control, and according to the American Diabetes Association, someone who has a level of 6.5 percent or higher has diabetes. The study did not differentiate between type 1 and type 2 diabetes.
In addition to finding that nearly one in three people with diabetes has some form of diabetic retinopathy, the researchers also found that slightly more men than women have the disease (about 32 percent versus 26 percent), and blacks and Mexican Americans have a higher rate of the disorder than whites (about 39, 34 and 26 percent, respectively).
Other risk factors for diabetic retinopathy found in the study included a higher A1C level (which indicates poor blood sugar control), higher systolic blood pressure, a longer duration of diabetes and insulin use.
Zhang said that many of these risk factors, such as a high A1C or the need for insulin (in type 2 diabetics) might indicate more severe diabetes, which is more likely to result in diabetic retinopathy.
”I was surprised to see that there’s still such a high prevalence of diabetic retinopathy,” said Dr. Richard Bergenstal, president of medicine and science for the American Diabetes Association. “We’ve made a lot of progress in treating diabetes and the hope is always that the complications are going away, but we still have a lot of people who aren’t quite to goal in terms of blood sugar management.”
Bergenstal said that everyone with type 2 diabetes should have a dilated eye exam soon after they’re diagnosed with diabetes, because they’ve likely had diabetes for a while without knowing it. After the initial exam, he said, a dilated eye exam is needed every year thereafter. People just diagnosed with type 1 diabetes may be able to wait a few years before having their first dilated eye exam, but then should have one every year after as well.
Bergenstal said that to help prevent retinopathy, people with either type of diabetes need to maintain good blood sugar levels, keep their blood pressure controlled, and lower their cholesterol with medications, if necessary.
Lack of Food Puts Kids at Risk for Asthma, Other Chronic Ills
Friday, August 13th, 2010Children and youth who don’t have enough to eat are at increased risk of poor health, and repeated episodes of hunger may put them at risk for chronic diseases such as asthma, researchers say.
The finding is from an analysis of data from a Canadian survey of 5,809 children aged 10 to 15 years and 3,333 youth aged 16 to 21 years, which was conducted from 1994 to 2004-2005.
During that time, 3.3 percent of children and 3.9 percent of youth experienced hunger at some point and 1.1 percent of children and 1.4 percent of youth went hungry on two or more occasions, the study found.
In the final round of the survey, 13.5 percent of children and 28.6 percent of youth reported poor health. Rates of poor health among those who’d experienced hunger at some point were higher than among those who had never gone hungry (32.9 percent of children and 47.3 percent of youth who had gone hungry were in poor health, compared with 12.8 percent of children and 27.9 percent of youth who had not).
The researchers also found that youth who went hungry more than once during the survey were at increased risk for asthma and other chronic illnesses.
Sharon Kirkpatrick, of the University of Calgary in Alberta, Canada, at the time of the study and now at the U.S. National Cancer Institute in Bethesda, Md., and colleagues published their findings in the August issue of the journal Archives of Pediatrics & Adolescent Medicine.
In 2008, about 15 percent of American households were affected by food insecurity, defined by the researchers as running out of food or lacking the money to buy food. That’s an increase from 11 percent in 2007 and the highest rate since monitoring began in 1995, according to background information in the study.
”The mechanism by which childhood hunger negatively affects health is not well understood,” Kirkpatrick’s team wrote. “Food insecurity has been associated with emotional and psychological stress among children, which could exert a negative effect on general health and contribute to heightened risk of chronic diseases.”
The findings add to evidence that “hunger is a serious risk factor for long-term poor health among children and youth, pointing to the relevance of severe food insecurity as an identifiable marker of vulnerability,” the study authors concluded.
High Earners Who Munch Frequently at Work, Stay Healthier
Friday, August 13th, 2010WASHINGTON – People who earn more money are more likely to munch on muffins or chocolate bars while working, according to researchers at University of Texas at Austin.
What’s more, such people boost their chances of staying healthy – thanks to the regular munching.
Economist Daniel Hamermesh and his colleagues used data from the American Time Use Survey from the U.S. Bureau of Labor Statistics to reach the conclusion.
And they examined how much time Americans spend eating meals each day and how much time they spend “grazing” – snacking or drinking while working, watching TV or doing some other activity.
“When their time becomes more valuable, people substitute grazing for eating, essentially switching to multi-tasking. Overall, better health is associated with more time spent eating, but especially with spreading that time over more meals per day,” said Hamermesh.
It was found that over fifty percent of all adults graze each day, with their grazing time almost equalling the time they spend eating meals.
The average American adult spends about two-and-a-half hours eating or grazing every day.
The study also revealed that men graze less but spend more time eating meals than women. Overall, men spend about three-and-a-half more minutes a day eating meals than women.
It was also found that better-educated people eat more frequently, spend more total time eating, graze more frequently and spend more total time grazing than those with less education.
Higher earners also spend more time eating individual meals, graze more frequently and spend more time during each individual grazing episode.
Those who spend more time eating have a lower body mass index (BMI), on average, and view themselves as healthier than those who spend less time eating.
Critical Gene for Brain Development, Mental Retardation Identified
Wednesday, August 11th, 2010WASHINGTON – Researchers at the University of North Carolina at Chapel Hill School of Medicine have discovered that a brain protein, called srGAP2, plays a vital role in brain development and could even lead to mental retardation.
Any flaw while establishing the neural circuitry of the developing brain could result in neurodevelopmental disorders such as mental retardation, dyslexia or autism.
Researchers have now discovered that establishing the neural wiring necessary to function normally depends on the ability of neurons to make finger-like projections of their membrane called filopodia.
And the finding indicates that the current notion regarding how cells change shape, migrate or differentiate needs to be revisited.
Senior study investigator Dr. Franck Polleux said that scientists have thought that the only way for a cell to morph and move is through the action of the cytoskeleton or the scaffold inside the cell, pushing membrane forward or sucking it in.
But his study has shown that the brain protein srGAP2 can also impose cell shape by directly bending membranes, forming filopodia as a mean to control the migration and branching of neurons during brain development.
Interestingly, srGAP2 is one of a family of proteins that have been implicated in a severe mental retardation syndrome called the 3p- syndrome.
Therefore this research could also yield important insights into the underlying causes of this and other forms of mental retardation.
Polleux and his colleagues began looking at srGAP2 because the gene was almost exclusively “turned on” or expressed during brain development.
The researchers focussed on the F-BAR domain, one of the handful of similarly termed “BAR domains” in the brain protein.
These unique domains are small functional chunks of protein sequence that may be common to other proteins as well.
The researchers were among the first to master a laboratory technique that enabled them to manipulate which genes are turned on or off in neurons, a notoriously difficult cell type.
Working with slices of mouse brain, they used electrical current to introduce pieces of genetic material that would either ramp up or, conversely, knock down the action of the protein’s F-BAR domain.
They then cultured brain slices in petri dishes allowing researchers to watch how the neurons behaved ‘in the wild’ in their native environment.
After ramping up the activity of the domain, they saw that the neurons formed the finger-like filopodia which blocked migration by inducing too many branches.
“The textbook notion is that F-BAR proteins fold inward, but here we show it can do the opposite. This is a completely novel mechanism for producing filopodia,” said Polleux.
The researchers then found that when they reduced the expression of this protein, the neurons migrated at a faster rate and branched less.
Second Child Within A Year Increases Breast Cancer Risk
Wednesday, August 11th, 2010LONDON – Having a second child within a year of the first birth can increase a woman’s risk of developing breast cancer, finds a new study.
The research, involving 30,000 women each of whom had produced five or more children, has shown that those with a gap of less than 12 month were 5.2 times more likely to develop the advanced ductal breast cancer than women who had a gap of three or more years.
Although it is unclear that why the risk increases, researchers believe hormones might be involved.
Alternatively, other risk factors may have influenced the results, including being overweight, and whether or not the mother chooses to breast-feed.
“Women who had their first two births close together should not be worried by these findings because the study’s results are not conclusive,” the Telegraph quoted Josephine Querido, senior science information officer at Cancer Research UK, as saying.
“The researchers looked at a very specific group of women – those who had a specific type of breast cancer, who had advanced tumours, who were under 50, and who had at least five children. In studies like this, dividing the group of people you’re looking at into lots of smaller groups makes it likely that you’ll find a positive result in one of the subgroups just by chance.
“For all women, it’s important to go to the GP if they spot any unusual changes in their breast, and to go for screening when invited,” Querido added.
The study appears in the British Journal of Cancer.
Aromatherapy
Wednesday, August 11th, 2010What is aromatherapy?
Aromatherapy is the use of essential oils from plants for healing. Although the word “aroma” makes it sound as if the oils would be inhaled, they can also be massaged into the skin or — rarely — taken by mouth. Essential oils should never be taken by mouth without specific instruction from a trained and qualified specialist. Whether inhaled or applied on the skin, essential oils are gaining new attention as an alternative treatment for infections, stress, and other health problems. However, in most cases scientific evidence is still lacking.
What are essential oils?
Essential oils are concentrated extracts taken from the roots, leaves, seeds, or blossoms of plants. Each contains its own mix of active ingredients, and this mix determines what the oil is sued for. Some oils are used to promote physical healing — for example, to treat swelling or fungal infections. Others are used for their emotional value — they may enhance relaxation or make a room smell pleasant. Orange blossom oil, for example, contains a large amount of an active ingredient that is thought to be calming.
What is the history of aromatherapy?
Essential oils have been used for therapeutic purposes for nearly 6,000 years. The ancient Chinese, Indians, Egyptians, Greeks, and Romans used them in cosmetics, perfumes, and drugs. Essential oils were also commonly used for spiritual, therapeutic, hygienic, and ritualistic purposes.
More recently, René-Maurice Gattefossé, a French chemist, discovered the healing properties of lavender oil when he applied it to a burn on his hand caused by an explosion in his laboratory. He then started to analyze the chemical properties of essential oils and how they were used to treat burns, skin infections, gangrene, and wounds in soldiers during World War I. In 1928, Gattefossé founded the science of aromatherapy. By the 1950s massage therapists, beauticians, nurses, physiotherapists, doctors, and other health care providers began using aromatherapy.
Aromatherapy did not become popular in the United States until the 1980s. Today, many lotions, candles, and beauty products are sold as “aromatherapy.” However, many of these products contain synthetic fragrances that do not have the same properties as essential oils.
How does aromatherapy work?
Researchers are not entirely clear how aromatherapy may work. Some experts believe our sense of smell may play a role. The “smell” receptors in your nose communicate with parts of your brain (the amygdala and hippocampus) that serve as storehouses for emotions and memories. When you breathe in essential oil molecules, some researchers believe that they stimulate these parts of your brain and influence physical, emotional, and mental health. For example, lavender is believed to stimulate the activity of brain cells in the amygdala similar to the way some sedative medications work. Other researchers think that some molecules from essential oils may interact in the blood with hormones or enzymes.
Aromatherapy massage is a popular way of using essential oils because it works in several ways at the same time. Your skin absorbs essential oils and you also breathe them in. Plus, you experience the physical therapy of the massage itself.
What happens during an aromatherapy session?
Professional aromatherapists, nurses, physical therapists, pharmacists, and massage therapists can provide topical or inhaled aromatherapy treatment. Only specially trained professionals can provide treatment that involves taking essential oils by mouth.
At an aromatherapy session, the practitioner will ask about your medical history and symptoms, as well any scents you may like. You may be directed to breathe in essential oils directly from a piece of cloth or indirectly through steam inhalations, vaporizers, or sprays. The practitioner may also apply diluted essential oils to your skin during a massage. In most cases, the practitioner will tell you how to use aromatherapy at home, by mixing essential oils into your bath, for example.
What is aromatherapy good for?
Aromatherapy is used in a wide range of settings — from health spas to hospitals — to treat a variety of conditions. In general, it seems to relieve pain, improve mood, and promote a sense of relaxation.
Several clinical studies suggest that when essential oils (particularly rose, lavender, and frankincense) were used by qualified midwives, pregnant women felt less anxiety and fear, had a stronger sense of well-being, and had less need for pain medications during delivery. Many women also report that peppermint oil relieves nausea and vomiting during labor.
Massage therapy with essential oils (combined with medications or therapy) may benefit people with depression. The scents are thought by some to stimulate positive emotions in the area of the brain responsible for memories and emotions, but the benefits seem to be related to relaxation caused by the scents and the massage. A person’ s belief that the treatment will help also influences whether it works.
In test tubes, chemical compounds from some essential oils have shown antibacterial and anti-fungal properties. Some evidence also suggests that citrus oils may strengthen the immune system and that peppermint oil may help with digestion. Fennel, aniseed, sage, and clary-sage have estrogen-like compounds, which may help relieve symptoms of premenstrual syndrome and menopause. However, human studies are lacking.
Other conditions for which aromatherapy may be helpful include:
- Alopecia areata (hair loss)
- Agitation, possibly including agitation related to dementia
- Anxiety
- Constipation (with abdominal massage using aromatherapy)
- Insomnia
- Pain: Studies have found that people with rheumatoid arthritis, cancer (using topical chamomile), and headaches (using topical peppermint) require fewer pain medications when they use aromatherapy
- Itching, a common side effect for those receiving dialysis
- Psoriasis
Should anyone avoid aromatherapy?
Pregnant women, people with severe asthma, and people with a history of allergies should avoid all essential oils.
Pregnant women and people with a history of seizures should avoid hyssop oil.
People with high blood pressure should avoid stimulating essential oils such as rosemary and spike lavender.
People with estrogen-dependent tumors (such as breast or ovarian cancer) should not use oils with estrogen-like compounds such as fennel, aniseed, sage, and clary-sage.
People receiving chemotherapy should talk to their doctor before trying aromatherapy.
Is there anything I should watch out for?
Most topical and inhaled essential oils are generally considered safe. You should never take essential oils by mouth unless you are under the supervision of a trained professional. Some oils are toxic, and taking them by mouth could be fatal.
Rarely, aromatherapy can induce side effects, such as rash, headache, liver and nerve damage, as well as harm to a fetus.
Oils that are high in phenols, such as cinnamon, can irritate the skin. Add water or a base massage oil (such as almond or sesame oil) to the essential oil before applying to your skin. Avoid using near your eyes.
Essential oils are highly volatile and flammable so they should never be used near an open flame.
Animal studies suggest that active ingredients in certain essential oils may interact with some medications. Researchers don’ t know if they have the same effect in humans. Eucalyptus, for example, may cause certain medications, including pentobarbital (used for seizures) and amphetamine (used for narcolepsy and attention-deficit hyperactivity disorder) to be less effective.
How can I find an aromatherapist?
While there are currently no boards that certify or license aromatherapists in the United States, many professionals are members of professional organizations. To locate a qualified aromatherapist in your area, contact the National Association of Holistic Therapy at www.naha.org. Many aromatherapists are trained in some other form of therapy or healing system, such as massage or chiropractic, and include aromatherapy in their practice.
What is the future of aromatherapy?
Although essential oils have been used for centuries, few studies have looked the safety and effectiveness of aromatherapy in people. Scientific evidence is lacking. And there are some concerns about the safety and quality of certain essential oils. More research is needed before aromatherapy becomes a widely accepted alternative remedy.
A Nap Can Make You Smarter
Wednesday, August 11th, 2010Instead of being viewed as lazy or slackers, workers who catch 40 winks in the afternoon may be gaining a bit more respect or at least a bit more understanding. Researchers from the University of California, Berkeley, found that napping an hour can dramatically restore and boost your brain power. Amazingly, they found a nap can actually make you smarter.
On the other hand, the more hours we spend awake, the more sluggish our minds become. These findings should give pause to college students who pull “all nighters” cramming for finals. The new study found this practice decreases the ability to learn by nearly 40 percent.
“Sleep not only rights the wrong of prolonged wakefullness, but at a neurocognitive level, it moves you beyond where you were before you took a nap,” Matthew Walker, an assistant professor of psychology at UC Berkeley and lead investigator, said in a statement.
In the study, 39 healthy young adults were divided into two groups nap and no-nap. Both groups were given rigorous learning tasks at noon to stress the hippocampus, a region of the brain that helps store fact-based memories. Results in both groups were similar.
At 2 p.m., the first group napped for 90 minutes while the no-nap group stayed awake. At 6 p.m., both groups were subjected to a new series of learning exercises. Those who napped performed markedly better and actually improved their ability to learn.
Walker said researchers believe sleep is needed to clear the brain’s short-term memory storage and make room for new information.
“It’s as though the e-mail inbox in your hippocampus is full and, until you sleep and clear out those fact e-mails, you’re not going to receive any more mail. It’s just going to bounce until you sleep and move it into another folder,” Walker said.
In addition to boosting your brain power, one study showed that napping can reduce the risk of a fatal heart attack by 37 percent.
Use these five tips for an effective, refreshing afternoon nap:
The best naptime is 1 p.m. until 3 p.m. when you experience a natural dip in energy.
Get comfortable. If you have a couch or comfy chair, use them, says Salary.com. Otherwise, stash a yoga mat and pillow behind your desk.
Draw the shades and wear a sleep mask to stimulate melatonin, a sleep-inducing hormone, advises Body Ecology.
Your body temperature may fall during sleep, so cover yourself with a light blanket.
Set an alarm to make sure you don’t oversleep.
How To Boost Your Libido Naturally
Wednesday, August 11th, 2010Knowing how to boost your metabolism naturally can offer great health benefits in addition to romantic activity. Nutrition plays an important role in desire and exercise can come into play when it comes to energy levels. Certain medical conditions can cause a decrease in libido, so it is important to discuss the symptom with your physician.
Medical conditions that are linked to low libido are not always serious in nature but the condition can be a symptom of a serious health condition. Treating any underlying medical condition can help create balance, naturally improving energy levels and sex drive. Some problems that can interfere include:
• Mood disorders
• Chronic fatigue
• Heart problems
• Diabetes
• Hormone imbalance
• Menopause
Any medical condition that interferes with hormone production, mood, or energy levels can have an effect on libido.
Mental Processing
The first step in the process is to address any mental processing problems that may interfere with the condition. In some cases, the loss of libido is psychological in nature, and it can stem from lack of confidence, disinterest in your partner, or feelings of guilt or inadequacy. Addressing these issues can naturally boost libido.
Focusing on positive aspects of yourself and your partner can help. Boosting your mood with sensual mental images throughout the day is an excellent visualization exercise that can help. Thoughts and feelings are closely linked, but few recognize that exercise and mental processing are closely related as well.
Exercise
Exercise helps libido in many ways. It boosts energy and it improves circulation. In addition, it helps to tone and tighten the body, and this can alleviate some feelings of oneself-consciousness in some individuals. Any activity that gets the blood flowing can improve circulation and improve sex drive.
Nutrition
Adding healthy foods to your daily menu can offer excellent benefits as well. Consider some of the following foods, some of which are considered to be aphrodisiacs.
• Cinnamon and nutmeg work in a number of ways. The aroma of these spices can enhance desire, and nutmeg has been shown to work much like Viagra in animal studies.
• Chocolate is a natural choice because it sets off the same chemicals in the brain that are released when a person falls in love. Phenylethylalamine is the helpful chemical in this natural aphrodisiac.
• Figs offer high levels of amino acids believed to help increase energy.
• Almonds contain healthy fats that improves brain function, promoting alert attention.
• Avocados contain essential fatty acids as well. This food is traditionally associated with sensuality.
• Oysters in the half shell are other foods closely associated with sensuality. This food contains lots of zinc, an element effective in improving male performance.
• Chili peppers can promote circulation; working much like exercise does to improve overall body performance.
In addition to the suggestions here, Discovery Health offers 10 ways to boost libido naturally. Combining different approaches is the ideal way to improve your health as well as your drive.
Brain Can Be Trained
Wednesday, August 11th, 2010Training and experience can affect how a person’s brain is organised, says a US study that compared 20 music conductors and 20 people with no music training.
All the participants were between the ages of 28 and 40. The conductors had an average of more than 10 years experience as a band or orchestra director in middle or high school.
The researchers used functional magnetic resonance imaging (fMRI) to monitor the participants’ brain activity while they performed a difficult hearing task that involved listening for two tones. They had to keep their eyes opened while doing the task.
Experience and brain functioning
Initially, both the conductors and non-musicians showed reduced activity in the brain’s visual processing area and increased activity in the auditory part of the brain. But as the task became harder, only the non-musicians tuned out more of their visual sense. This suggests that the conductors’ music training and experience altered the way their brains work, the researchers said.
“Because the task was equally difficult for everybody, the difference observed between conductors and non-musicians must be related to a change in how they deal with irrelevant sensory information and not just their ability to do the task,” lead author W. David Hairston, a postdoctoral fellow in radiology at the Advanced Neuroscience Imaging Research Laboratory at Wake Forest University Baptist Medical Centre in Winston-Salem, N.C., said in a prepared statement.
“In general, based on the non-musicians, we suggest that the brain actively increases how much information from other senses gets filtered out or ignored when you have to concentrate really hard on one sense,” Hairston said.
Brain adapts
He noted that conductors routinely must differentiate between subtle differences in sounds and often have to do this while reading scores and watching/communicating with their musicians. This leads to an ability to focus on a difficult auditory task without having to increase suppression of visual information.
The study results “show how the brain filters information from different senses is very flexible and adaptive and changes with the demands of the task at hand. Additionally, how this operates can change with highly specialized training and experience,” Hairston said.
Communication Gap Seen Between Patients, Doctors
Wednesday, August 11th, 2010What doctors think they are telling hospital patients, and what those patients actually hear, may be very different, a small study suggests.
The findings, from a study of 89 patients at one U.S. hospital, add to research showing that doctors and patients are often not on the same page when discussing diagnoses and treatment.
In interviews with the patients on the day of their discharge, researchers found that only 18 percent even knew the name of the main physician in charge of their hospital care. Meanwhile, just 57 percent left the hospital knowing what their diagnosis was.
In contrast, two-thirds of the 43 physicians interviewed thought their patients knew their name, and 77 percent believed their patients were aware of their diagnosis.
Drs. Douglas P. Olson and Donna M. Windish of Yale University School of Medicine in New Haven, Connecticut, report the results in the Archives of Internal Medicine.
The finding that many patients were unsure of their diagnosis or their doctor’s name may sound surprising, but it is not new, according to Olson. Past studies have found that the majority of hospital patients cannot name their main physician, and frequently cannot name their medical problem.
However, the current study also shows that many doctors mistakenly believe their patients know more than they do.
“What’s new here is the discrepancy between doctors and patients,” Olson told Reuters Health. “Patients aren’t really getting the take-home message.”
The communication gaps go beyond names and diagnoses, the study found. Of patients in this study who were prescribed a new medication during their hospital stay, one-quarter said their doctor never told them about it. And very few — 10 percent — said their doctor discussed the drug’s potential side effects with them.
In contrast, all physicians in the study said they at least sometimes told patients about any new prescriptions, and 81 percent said they described the possible side effects at least some of the time.
In recent years, the medical community has increasingly focused on improving doctor-patient communication. In residency programs at academic hospitals, for instance, doctors-in-training are taught to include patients in discussions rather than talking amongst themselves in front of patients, Olson pointed out.
“But there’s still a disconnect,” he said, adding that even when patients say they understand, that often turns out not to be the case.
One explanation, according to Olson, may be that many hospitalized patients are elderly and have complex medical problems — not just one diagnosis, but several co-existing health conditions — and the information they receive during their stay “could understandably be overwhelming.”
And compared with 30 or 40 years ago, Olson noted, patients’ hospital stays are now typically much shorter; that leaves them with less time to absorb and fully understand information about their condition and any treatment changes.
One potential way to address the communication gaps would be to give patients and families written information, in addition to spoken explanations, during the hospital stay — and not only at discharge, Olson said.
“It’s important for us to take a step back and see how some system changes might improve communication,” he said.
Steps patients and their family members can take include writing down any questions as they come up so they can raise them with the doctor later, according to Olson.
Family involvement is important, he noted, particularly for older patients with more complex medical problems and multiple medications.
“How is my life going to be different when I leave the hospital?” is a good general question that patients can ask their doctors, Olson recommends. It can help start a discussion about a range of concerns, including any lifestyle adjustments and medication changes that need to be made, he said.
Olson also advised that patients lacking a primary care doctor get the number of someone at the hospital whom they can call with any questions after they are discharged.
Cancer Cells Slurp Up Fructose, US study finds
Tuesday, August 10th, 2010Pancreatic tumor cells use fructose to divide and proliferate, U.S. researchers said on Monday in a study that challenges the common wisdom that all sugars are the same.
Tumor cells fed both glucose and fructose used the two sugars in two different ways, the team at the University of California Los Angeles found.
They said their finding, published in the journal Cancer Research, may help explain other studies that have linked fructose intake with pancreatic cancer, one of the deadliest cancer types.
“These findings show that cancer cells can readily metabolize fructose to increase proliferation,” Dr. Anthony Heaney of UCLA’s Jonsson Cancer Center and colleagues wrote.
“They have major significance for cancer patients given dietary refined fructose consumption, and indicate that efforts to reduce refined fructose intake or inhibit fructose-mediated actions may disrupt cancer growth.”
Americans take in large amounts of fructose, mainly in high fructose corn syrup, a mix of fructose and glucose that is used in soft drinks, bread and a range of other foods.
Politicians, regulators, health experts and the industry have debated whether high fructose corn syrup and other ingredients have been helping make Americans fatter and less healthy.
Too much sugar of any kind not only adds pounds, but is also a key culprit in diabetes, heart disease and stroke, according to the American Heart Association.
Several states, including New York and California, have weighed a tax on sweetened soft drinks to defray the cost of treating obesity-related diseases such as heart disease, diabetes and cancer.
The American Beverage Association, whose members include Coca-Cola (KO.N) and Kraft Foods (KFT.N) have strongly, and successfully, opposed efforts to tax soda. [ID:nN12233126]
The industry has also argued that sugar is sugar.
Heaney said his team found otherwise. They grew pancreatic cancer cells in lab dishes and fed them both glucose and fructose.
Tumor cells thrive on sugar but they used the fructose to proliferate. “Importantly, fructose and glucose metabolism are quite different,” Heaney’s team wrote.
“I think this paper has a lot of public health implications. Hopefully, at the federal level there will be some effort to step back on the amount of high fructose corn syrup in our diets,” Heaney said in a statement.
Now the team hopes to develop a drug that might stop tumor cells from making use of fructose.
U.S. consumption of high fructose corn syrup went up 1,000 percent between 1970 and 1990, researchers reported in 2004 in the American Journal of Clinical Nutrition.
High-BMI Teens Risk Hypertension
Monday, August 9th, 2010Study suggests those with “normal blood pressure” still at risk.
The body mass index (BMI) of seemingly healthy teens in 11th or 12th grade should be checked to predict whether they are likely to develop hypertension (high blood pressure) as young adults. This is the lesson of a new study by Ben-Gurion University of the Negev researchers who just published their findings in the journal Hypertension of the American Heart Association.
The BMI can easily be calculated by dividing one’s weight in kilos by the square of one’s height in meters (or in non-metric countries, the number of pounds multiplied by 703 and divided by one’s height in inches squared). Anyone with a BMI over 25 is considered overweight; if it is over 30, the person is obese.
BGU clinical biochemistry Prof. Assaf Rudich, who headed the large-scale prospective study, said that despite “normal” blood pressure at age 17, hypertension can develop a few years later. The team also found that teenage boys are three to four times more likely to develop high blood pressure in early adulthood than girls.
Currently, systolic blood pressures (the top number of the reading) of 100 to 110 and even up to 120 are considered within the normal range for adolescents. But if their BMI is too high, they may be in trouble and having a lower blood pressure at 17 should now be regarded as desirable, Rudich said.
Known as the “silent killer,” hypertension is a major risk factor for heart disease and vascular diseases like stroke, he said. “It is increasing along with the obesity epidemic, but regrettably young adults who are otherwise healthy frequently are not screened for becoming hypertensive.”
The BGU researchers examined the development of blood pressure from adolescence to young adulthood in 23,191 men and 3,789 women from the ages of 17 when undergoing medical tests for the Israel Defense Forces and followed them up until the age of 42. They took regular readings of blood pressure and BMI of teenagers who did not have high blood pressure at 17.
The study showed that in boys, there is a strong correlation between blood pressure and BMI at 17, meaning that while the blood pressure reading may be in the “normal range,” there is a greater risk for hypertension when BMI is also evaluated.
The rate of progression to hypertension is higher in boys whose systolic blood pressure is 110 versus those whose blood pressure is 100.
For girls, only the sub-group considered obese had substantially higher risk of high blood pressure. The researchers believe that the hormone estrogen may protect against hypertension.
The study also confirmed the observation that 17-year-old boys have higher blood pressure than girls of the same age. During a follow-up period with these adolescents, 14 percent or 3,810 people developed hypertension.
“Collectively, the study suggests that pediatricians caring for adolescents and physicians caring for young adults should be more aware of the need to monitor weight and blood pressure even when they are considered normal,” said Prof. Iris Shai of the Faculty of Health Sciences‚ epidemiology department.
“For the individual person, a ‘normal value’ may still be associated with a significant elevated risk of disease when the BMI and sex of the patient is also considered,” she concluded.
Personality Set for Life By 1st Grade
Monday, August 9th, 2010Our personalities stay pretty much the same throughout our lives, from our early childhood years to after we’re over the hill, according to a new study.
The results show personality traits observed in children as young as first graders are a strong predictor of adult behavior.
“We remain recognizably the same person,” said study author Christopher Nave, a doctoral candidate at the University of California, Riverside. “This speaks to the importance of understanding personality because it does follow us wherever we go across time and contexts.”
The study will be published in an upcoming issue of the journal Social Psychological and Personality Science.
Using data from a 1960s study of approximately 2,400 ethnically diverse schoolchildren (grades 1 – 6) in Hawaii, researchers compared teacher personality ratings of the students with videotaped interviews of 144 of those individuals 40 years later.
They examined four personality attributes – talkativeness (called verbal fluency), adaptability (cope well with new situations), impulsiveness and self-minimizing behavior (essentially being humble to the point of minimizing one’s importance).
Among the findings:
Talkative youngsters tended to show interest in intellectual matters, speak fluently, try to control situations, and exhibit a high degree of intelligence as adults. Children who rated low in verbal fluency were observed as adults to seek advice, give up when faced with obstacles, and exhibit an awkward interpersonal style.
Children rated as highly adaptable tended, as middle-age adults, to behave cheerfully, speak fluently and show interest in intellectual matters. Those who rated low in adaptability as children were observed as adults to say negative things about themselves, seek advice and exhibit an awkward interpersonal style.
Students rated as impulsive were inclined to speak loudly, display a wide range of interests and be talkative as adults. Less impulsive kids tended to be fearful or timid, kept others at a distance and expressed insecurity as adults.
Children characterized as self-minimizing were likely to express guilt, seek reassurance, say negative things about themselves and express insecurity as adults. Those who were ranked low on a self-minimizing scale tended to speak loudly, show interest in intellectual matters and exhibit condescending behavior as adults.
Changing personality
Previous research has suggested that while our personalities can change, it’s not an easy undertaking.
Personality is “a part of us, a part of our biology,” Nave said. “Life events still influence our behaviors, yet we must acknowledge the power of personality in understanding future behavior as well.”
Future research will “help us understand how personality is related to behavior as well as examine the extent to which we may be able to change our personality,” Nave said.
Patients Experience Faster Recuperation With Healing Touch
Saturday, August 7th, 2010Greenwich Hospital surgical, labor and delivery, and oncology patients are among those who have received a healing boost through a form of energy therapy known as Healing Touch.
The hospital, known for its reputation of service excellence, is among a growing number of medical facilities utilizing Healing Touch, which is a gentle, noninvasive therapy shown to facilitate the relaxation response to enhance the healing process. Research shows that, in addition to inducing a deep sense of calm and relaxation, Healing Touch helps to reduce pain, decrease anxiety, promote sleep and improve an overall sense of well-being.
Healing Touch trained volunteers, gently place their hands on or above a person’s “energy centers” of the body. The patient is fully clothed. The goal is to strengthen the body’s ability to heal itself by restoring balance and harmony to the body’s energy system.
Energy healing therapy involves the channeling of healing energy through the hands of a practitioner into the patient’s body to restore normal energy balance and, therefore, health, as described by the National Institutes of Health’s National Center for Complementary and Alternative Medicine.
Greenwich Hospital offers Healing Touch to inpatients. The service is also provided by Greenwich Hospital’s Center for Integrative Medicine in Cos Cob, Connecticut. Certified practitioners from the Center are also available to offer Healing Touch in a patient’s home, in corporations and in schools.
Five Million California Adults Say They Are Mentally Stressed
Saturday, August 7th, 2010Almost 5 million California adults say they could use help with a mental or emotional problem, according to a survey released Wednesday by researchers at UCLA. About 1 million of them meet the criteria for “serious psychological distress.”
However, only one in three people who perceive a need for mental health services or are in serious distress have seen a professional for treatment, the survey found.
The survey was conducted among more than 44,000 adults as part of the 2005 California Health Interview Survey, administered through the UCLA Center for Health Policy Research. Since the survey was conducted, the recession probably has contributed to worsening mental health for even more people, said the lead author of the study, David Grant.
The survey showed that lack of health insurance coverage was a major reason why people didn’t seek help — a situation that may be rectified somewhat by state and national mental health parity laws now in effect that require insurers to cover mental health conditions similarly to they way they cover physical conditions. (The final phase of the federal law went into effect on July 1.) However, stigma continues to be a barrier to mental health services. The survey found that men, people 65 and older, Latinos and Asians were less likely to seek help because of the stigma associated with mental or emotional problems. But being poor is the biggest barrier to care.
According to the survey:
- Women were nearly twice as likely as men to say they needed help because they felt sad, anxious or nervous (22.7% compared to 14.3%).
- Adults under age 65 were twice as likely to perceive the need for help (20.2% compared to 9.2%).
- The poorest adults were more than five times as likely to report symptoms of serious psychological distress compared to those living well above the federal poverty level.
“The findings also demonstrate a crucial need for continued efforts to expand mental-health services and to meet threats to such services caused by the ongoing state budget crisis in Sacramento; reduced state funding for local mental health programs and public insurance programs could be devastating to hundreds of thousands of Californians with mental health needs,” the authors wrote.
Mental health services always seems to be a big target when it comes to trimming state and local budgets. Lawmakers can get away with it, of course, because the stigma surrounding mental illness prevents people from protesting such cuts. Given the number of people in pain, according to this survey, it may be time for Californians to overcome the perceived stigma and demand expanded public funding and insurance coverage of mental health care.
Two New Types of “Bad” Cholesterol Discovered This Year
Saturday, August 7th, 2010Scientists have discovered a second “new” form of “bad” cholesterol they say can contribute to heart disease.
Lipoprotein(a), or Lp(a), apparently does not respond to diet or cholesterol medication – but neither does it carry the same risk as the first-generation “bad” cholesterol, LDL.
According to the findings of a study reported this month in the New England Journal of Medicine, lead author Professor Martin Farrall said Lp(a) appears to upset the blood-clotting process. The study, funded by the British Heart Foundation, used gene-chip technology to scan DNA that had previously been identified to contain potential risk areas for heart disease. Two genetic factors were identified.
Nonetheless, Farrall emphasized that “the increase in risk to people from high Lp(a) levels is significantly less severe that the risk from high LDL cholesterol levels. So Lp(a) doesn’t trump LDL, which has a larger impact and which we can already control pretty effectively.” The aim, he added, is to find a medication that will simultaneously control both.
Newer Cholesterol Culprit Identified Earlier
Another new form of “bad” cholesterol was identified earlier this year by a researcher at the Chinese University of Hong Kong. Khen-Yu Chen, Ph.D. presented his findings at the 238th National Meeting of the American Chemical Society earlier in the year.
In an interview published by Science Daily this past August, Chen said oxycholesterol – which at present also cannot be controlled by diet or current medications on the market — might turn out to be the most serious threat of all to cardiovascular health.
Oxycholesterol was proved to reduce the elasticity of arteries and impaired their ability to expand and carry more blood throughout the body. It also produced more deposits of cholesterol in the lining of arteries and a tendency to develop larger fatty deposits — atherosclerotic plaques — which increase the risk for heart attack and stroke.
“Our work demonstrated that oxycholesterol boosts total cholesterol levels and promotes atherosclerosis (hardening of the arteries) more than non-oxidized cholesterol,” Chen told Science Daily.
Foods containing high amounts of oxycholesterol include anything fried or highly processed, including the average “fast food.” Oxidation occurs when fatty foods are heated — so forget those griben treats (fried chicken morsels produced when rendering chicken fat) that older-generation Ashkenazi Jews love so much. Likewise the ubiquitous Israeli snack foods found on every street corner, the deep-fried chickpea balls known as felafel, and shnitzel — breaded and deep-fried fish or chicken cutlets.
The good news is that a diet rich in antioxidants can counter these effects, accordin to Chen, who said that antioxidants might block the process that forms oxycholesterol. Such a diet includes fresh fruit and vegetables, whole grains, nuts and seeds, and certain herbs and spices.
Coffee Extract Prevents Bad Breath
Saturday, August 7th, 2010
We all know why Starbucks puts boxes of breath mints close to the cash register. Your morning latte can create a startling aroma in your mouth, strong enough to startle your co-workers too.
But intriguing new research from Tel Aviv University by breath specialist Prof. Mel Rosenberg finds that a coffee extract can inhibit the bacteria that lead to bad breath. New laboratory tests have shown that the extract prevents malodorous bacteria from making their presence felt ― or smelt.
“Everybody thinks that coffee causes bad breath,” says Prof. Rosenberg, “and it’s often true, because coffee, which has a dehydrating effect in the mouth, becomes potent when mixed with milk, and can ferment into smelly substances.”
But not always: “Contrary to our expectations, we found some components in coffee that actually inhibit bad breath,” explains Prof. Rosenberg. The findings were presented last month to members of the International Society for Breath Odor Research in Germany by Yael Gov, a researcher in Prof. Rosenberg’s laboratory
A “taster’s choice” for stopping bad bacteria
In the laboratory, the team monitored the bacterial odor production of coffee in saliva. In the study, three different brands of coffee were tested: the Israeli brand Elite coffee, Landwer Turkish coffee, and Taster’s Choice. Prof. Rosenberg expected to demonstrate the malodor-causing effect of coffee in an in vitro saliva evaluation developed by Dr. Sarit Levitan in his laboratory. To his surprise, the extracts had the opposite effect.
“The lesson we learned here is one of humility,” says Prof. Rosenberg. “We expected coffee would cause bad breath, but there is something inside this magic brew that has the opposite effect.”
Prof. Rosenberg would love to isolate the bacterial-inhibiting molecule in order to reap the biggest anti-bacterial benefits from coffee. “It’s not the raw extract we will use,” he says, “but an active material within it.” His latest discovery could be the foundation for an entirely new class of mouthwash, breath mints and gum. Purified coffee extract can be added to a breath mint to stop bacteria from forming, stopping bad breath at its source, instead of masking the smell with a mint flavor.
Prof. Rosenberg previously developed a popular mouthwash sold widely in Europe, a pocket-based breath test, and an anti-odor chewing gum.


Children’s Sleep Changes May Mean ‘Terrible Teens’ On the Way
Saturday, August 7th, 2010A new study by a researcher at Tel Aviv University has found that when children begin to change their sleep patterns, adolescence may not be far behind.
The findings of the study by Professor Avi Sadeh of the Department of Psychology were reported in a recent issue of the journal Sleep. The study was supported by a grant from the Israel Science Foundation.
Over a two-year period, sleep onset was significantly delayed by an average of 50 minutes in 72 children age 10 and 11 at the start of the study. Sleep time was significantly reduced by an average of 37 minutes. Girls had higher sleep efficiency and reported fewer night awakenings than boys, but for both, initial levels of sleep predicted an increase in pubertal development over time.
The children who participated in the study (94 at the start and 72 by the time the study ended) kept sleep diaries and wore an actigraph on the wrist to measure biological functions. An initial assessment was taken at the beginning of the study, with a second and final assessment taken at one-year intervals.
According to Sadeh, the findings suggest that the neurobehavioral changes associated with puberty may be seen earlier in sleep organization than in bodily changes. However, he adds, “psychosocial issues such as school demands, social activities and technological distractions can also lead to the development of bad sleep habits.”
“It is very important for parents to be aware of the importance of sleep for their developing children and to maintain supervision throughout the adolescent years,” he says. “School health education should also provide children with compelling information on how insufficient sleep compromises their well-being, psychological functioning and school achievements.”
Sadeh also notes that as children become adolescents, they tend to go to bed later and get up later as well. They also sleep less, which is associated with daytime sleepiness, sleep less during the week and more during the weekend to compensate.
Significant differences were seen between sleep on Friday nights and school nights given that Israel has a six-day school week, with Friday the only day not followed by school.
On Fridays, sleep onset was delayed, sleep time extended and sleep quality poorer than on other nights. There was no difference between puberty status or gender, suggesting that the tendency to “catch up” on sleep over the weekend is steady throughout early adolescence.
Sadeh says the findings may have other implications as well. “A deeper understanding of the interrelationships between sleep and pubertal maturation may provide new insights into the emergence of vulnerabilities for behavioral and emotional health problems in early adolescence. This could improve prevention and early intervention efforts.”
Study; Residents of the United Arab Emirates Highly Sedentary
Saturday, August 7th, 2010A mere four percent on people living in the United Arab Emirates walk on a weekly basis, a new study by an international shoe maker has found.
Commissioned by South Korean shoe manufacturer RYN ahead of their forthcoming entrance into the Gulf shoe market, the study into Emiratis’ walking habits found that both UAE citizens and expatriates alike are not walking regularly enough.
In spite the fact that the walking infrastructure in the United Arab Emirates is well advanced compared to most countries in the world, just 4% of residents walk on a weekly basis,” read the report.
Dubai, the economic hub of the UAE, has built extensive pedestrian-friendly infrastructure, such as air conditioned walkways connecting major sites to encourage residents to walk instead of taking the car.
Dr. M. Ashfaq Konchwalla, Consultant Orthopaedic & Sports Surgeon at Dubai’s Medcare Hospital, said residents should take the study as a warning.
“Walking makes us live longer,” he told The Media Line. “Walking 150 minutes per week makes a person lose 7 percent of their body weight, which reduces risk of diseases.”
“Walking strengthens heart and is also good for the brain and the bones,” he continued. “It also helps alleviate symptoms of depression, improves fitness and enhances physical function.”
Gulf-based medical professionals say that the lack of exercise has led to a rise in lifestyle diseases such as obesity and diabetes.
“Six countries in the Middle East and North African Region are among the world’s 10 highest for diabetes prevalence, including the United Arab Emirates,” David Whiting, Epidemiologist and Public Health Specialist of the International Diabetes Federation told The Media Line. “The ageing of populations, together with socio-economic and lifestyle changes, has resulted in the dramatic increase in diabetes prevalence. To a large extent the rise in prevalence is the unintended side-effect of great success in recent years.”
Many Emiratis have stopped eating traditional foods, which are rich in fiber and plant protein, turning instead to a diet of animal protein, fried food and cream, all new ingredients in the local diet.
“Over the past three decades, major social and economic changes have occurred,” Whiting said. “These include progressive urbanization, decreasing infant mortality and increasing life expectancy.”
“Rapid economic development has been associated with tremendous modification in lifestyle towards the westernized pattern reflected by changes in nutrition, less physical activity, tendency to increased obesity and more smoking,” he added.
Recent statistics from the International Diabetes Federation place the United Arab Emirates with the second worst diabetes rate in the world, with 18.7% of the population suffering from the disease.
Saudi Arabia follows close behind with 16.8% of its adult population suffering from diabetes. Bahrain (15.4%) was ranked fifth, Kuwait (14.6%) seventh and Oman (13.4%) eighth.
How To Cope With a Crybaby
Saturday, August 7th, 2010Newborn infants don’t come with a user manual, but if they did, this 275-page, Hebrew-language volume could serve quite well. However, it should be given as a gift or purchased after delivery – as the user-friendly text gives so many details on babies’ sensitivity and how much care they need round the clock that reading it might discourage couples from having progeny at all.
Some people’s hearts skip a beat from even a single wail, while others are rather more resistant – but no mother can continue what she is doing with equanimity when her baby is screaming its lungs out and looking miserable. Women must be naturally wired to get upset by babies’ cries as an evolutionary tool to get them to pick the helpless creatures up.
The book was jointly written by two women, Sivan Ofiri and Irit Shaked, the first the mother of two and the second of four. Ofiri is a childbirth educator and doula (assistant who provides nonmedical support during and even after delivery) and leads courses for mothers and their babies, while Shaked describes herself as a supporter of parents after delivery who teaches baby massage.
While most of the advice they give is scientifically based, they include some techniques such as Bach flowers and other essences, chiropractic, craniosacral, homeopathy, osteopathy and other complementary medicine techniques that have not been scientifically proven to help reduce crying.
A Schneider Children’s Medical Center pediatrician who is also a homeopath writes in the foreword that the book – published among a wide variety of books for new parents – is original and spellbinding as a “first-aid” book and as general guidance for exhausted, frustrated parents. He claims it is unique because the two experienced women “integrate technical details with spiritual perceptions of the world and provide advice and ideas to help young parents who were never prepared for the job.”
Ofiri and Shaked note in their introduction that in an age of “instant solutions,” it is still not easy to understand why your baby is crying and how to help him. Existing information, they state, “ignores the real needs of babies and lack the basic understanding of who the baby is and what are his needs and abilities.” Too often, parents do not pay attention to their instincts and are influenced by other people and confusing information.
After “thousands of years of evolution,” they write, babies have not changed and still have the same needs, reflexes and instincts. “The role of crying is to protect the baby, he will be near his mother or another person and be cared for in the best possible way.
Crying is the communications medium of your baby with the world until you will learn to identify the signs he broadcasts or until he learns to speak and tell you himself what he wants.” But, followed more than 250 pages, this subject is much more complicated.
The story begins during, not after, pregnancy. The authors write that the fetus is easily influenced by the mother. When she is very stressed, she releases the stress hormone cortisol into her bloodstream that reaches the fetus via the placenta and can even induce it to excrete its own stress hormone. Babies whose mothers were very stressed during pregnancy are known to cry more than those born to women who were calm.
But the womb is generally the most peaceful place a baby will encounter. The fetus hears its mother’s (and even father’s) voice; getting food from the mother’s bloodstream through the placenta, it is never hungry; it floats calmly in the amniotic fluid; it is held closely and protected by the amniotic sac; and even early contractions are like a massage. While most other mammals can get up, dust themselves off and start walking or swimming after their mothers after birth, the human baby needs a lot more time to lose its helplessness, develop and make itself understood, hence the role of crying.
But if a baby’s delivery was traumatic – taking a lot time, with induction, the use of medication or an internal monitor attached to its scalp, a forceps or vacuum birth, a cesarean section or lack of oxygen – the baby’s behavior can be affected afterward, they write. Among the signs of trauma are an unevenly shaped head; one eye closed more than the other for some time; tightened lips even when it rests or sleeps; the inability to turn the head to either sides if lying on its stomach; crying when touched on its back, neck or head; difficulty or refusal to open the mouth; and throwing its head backward and arching its back.
If pressure was put during delivery on the upper spine and base of the skull, causing painful movements of the vertebrae, they write, these symptoms of trauma can appear. If the baby is delivered with instruments, the newborn may feel pain that persists for days. If there is a cesarean delivery, the baby may be “unprepared” and liquid may still be filling the lungs because no contractions pushed it out. The baby is suddenly and unnaturally pulled out of the womb; it is best that the mother hold it immediately and give it gentle massage, they advise. With a complementary medicine background, they suggest applying herbal essences such as Bach flowers or “Rescue Remedy” or even have him “manipulated” by a chiropractor, osteopath or craniosacral expert.
Whether the delivery was traumatic to the baby or not, the authors urge that if healthy, it be placed on the mother’s stomach for bonding and warmth and offered the breast. Being totally wrapped up so it cannot feel the warmth of its mother’s skin is not advisable if the delivery room is warm enough, they continue.
Injections and tests can almost always wait.
And when injections are necessary, the mother or father should hold the baby and talk: “Babies understand even if they can’t speak.” In addition, breastfeeding always calms the baby and relieves pain.
The book recommends rooming in rather than having the infants taken to the nursery to be cared for by busy nurses. Even though it is natural for mothers to want to rest after exhausting and painful labor, the first few days of life are best spent with the mother, they write. The baby feels more confident, is served immediately and will cry less. Mothers of low-birthweight premature babies, who may feel “guilt” or the blues for not carrying them to term, should best spend as much time with them as possible, touching and massaging them and carrying them around skinto- skin on their chests like a kangaroo in its mother’s pouches. “Kangaroo therapy” has been shown to speed growth and development and reduce crying later on. Massage therapy, which is easy to learn and taught in many hospitals, can help reduce pain and calm newborns and can be carried out even beyond the baby’s first birthday.
After discharge from the hospital, the mother will often feel frustrated by being unable to calm her baby even though he has been fed, diapered, bathed and burped. Crying can arouse “fear, anxiety, distress, despair, estrangement, loneliness, frustration, disappointment, a feeling of failure, depression, mercy, rejection, exhaustion, the need to protect, love, doubts, difficult, pressure, empathy, identification, a need for closeness, worry, confusion, bewilderment and – first and foremost – a forceful need to stop the crying.”
Remember, they write, that crying is natural, and that you are the only parents the baby knows. “He doesn’t compare you to anyone. For him, you are the best parents…
Remember that your baby will not cry forever.
This period, with all its difficulties, will pass. At the end of a difficult day, go to sleep knowing that tomorrow will be a new day that can be completely different.”
The authors advise parents not to leave an infant crying in the cradle when they have tried “everything” and nothing works. Being left alone without care can reduce babies’ self-confidence and decrease their trust in the parents and the world. The authors deny the popular notion that picking an infant up whenever he cries leads to him “becoming spoiled.”
For the baby to feel emotional and physical calm, “he needs the feeling that you are there for him in the full meaning of the word.” Not only the mother’s body releases the feel-good pleasure hormones oxytocin and opiates, the baby’s body does so as well. When the baby’s needs are met, these hormones can calm him and reduce tears.
Crying will usually be most intensive during the first three months, but some babies can be satisfied by feeding and diapering during that period and only later become crybabies. Crying usually comes on three basic forms at this age: a monotonous da-da-da that calls for the caregiver’s attention and means: “I feel lonely,” “I need a hug” or “Please pick me up.” The second type is much stronger and means: “I need help because I’m hungry, need a diaper change, have gas on the stomach or am frightened.” The third is a highoctave sudden cry that usually is a signal of pain. Even if there is no pain, crying can serve as a release of tension, they write. “You should try to find the source and deal with it immediately.”
The authors provide a variety of tips to parents when they seemed to have tried everything to end the crying: Wrapping newborns up in a light blanket up to the neck can give them the womb-like feeling of “being held”; making the sound shhhhhhhhhhhh is a familiar uterine sound and can work; turning on a metronome at a heartbeat’s pace can help; white noise from between radio stations or even a washing machine or hair drier is another possibility. Various holding positions and massage techniques that calm the baby are illustrated in word and photos. The baby naturally wants to suck, and if the breast or a pacifier doesn’t help, putting a very clean parental finger or even the baby’s own hand into the mouth may, they suggest, along with the possibility of a joint parent/baby bath. Talking to the baby face to face can also trigger his interest.
Physiological conditions such as colic, allergies, constipation and the appearance of the first tooth as causes of crying are also discussed in detail. Advice on how to take the baby out in the car, one parent alone or both, and on the roles of the father and babyminder are also provided. But the book does not cover crying throughout childhood. However, there is mention of toddler tantrums and how to cope with them; beyond that advice, one has best turn to Dr. Spock and his many successors.
Although Prof. Arthur Eidelman – one of the country’s most experienced neonatologists who for decades headed the neonatal unit and the pediatrics department at Jerusalem’s Shaare Zedek Medical Center – had not yet read the volume, he was willing to comment when the complementary medicine components were described to him. “Massage therapy and swaddling are definitely relaxing for babies and can reduce crying, and ‘kangaroo therapy’ is very beneficial for both premature and term babies. Acupuncture has been used for colic, and there is some scientific evidence that it can also relieve pain in older people.”
But all the other complementary medicine claims have no backing by scientific research, said Eidelman, and quality control is very variable. “Manipulation, homeopathy and floral essences to treat pain and reduce crying are a lot of nonsense. Nothing has been proven.” He added that they probably won’t cause harm when offered by a well-trained person, but they probably won’t help.
“Low-birthweight babies in general tend to be irritable, as they have low pain thresholds. Crying may also be due to what its breast-feeding mother eats or drinks – coffee, alcohol, medications and even chocolate – and whether she smokes,” he said. “But if nothing helps, parents should urgently take the baby to the doctor for an examination.”



