There is something seriously wrong in the fertile Yakima Valley region of Washington. A surging number of babies are being born with major birth defects, and the reasons why are eluding state health officials.
As reported by CNN, a nurse in the area, Sara Barron, was the first to report on a particularly Continue reading →
Ever since the biotechnology industry first made inroads into South America back in the 1990s, rates of birth defects, cancer and other illnesses have steadily increased, a direct result of pesticides and herbicides being sprayed near residential areas. And one group of mothers from Argentina, known as “Mothers of Ituzaingo,” is demanding that the industry’s largest player, Continue reading →
Of all the great gifts our Creator has given us, there is nothing that compares to the miracle of childbirth. Watching your child open his eyes and draw his first breath in this world is a magical and life-affirming experience that will bring you to tears.
But for many families, the birth of a child can also bring with it a terrifying, lingering question that I pray never Continue reading →
With most couples using personal lubricants and over 80% of women using sexual products, chances are that you and/or your partner(s) have encountered toxins in them. Most consumers are shocked to learn that because most sexual products are labeled as novelty items there are no regulations that would Continue reading →
A 2012 nutritional analysis of GMO versus non-GMO corn shows shocking differences in nutritional content. Non-GMO corn contains 437 times more calcium, 56 times more magnesium, and 7 times more manganese than GMO corn
Big Pharma wants pregnant women to take prescription drugs, vaccine shots and even chemotherapy. It’s the latest insanity from an industry that kills more Americans ever year than died in the entire Vietnam War. And the latest science reveals that antidepressant use during pregnancy is causing Continue reading →
Priority One of looking younger, as any doctor or anti-aging expert will tell you, is taking care of your skin: minimal sun exposure, hydration, supplements, and so on. But many people with the best of intentions are inadvertently exposing themselves to a battlefield of toxins waging war on the face and skin. Imagine slathering on a skin cream loaded with lead, parabens and Continue reading →
After the political tempest about Gardasil and mandatory HPV vaccinations, CNN posted an article about the things they claimed should be known. The article contended that the HPV vaccine controversy was mostly political and that HPV vaccines were safe. It also noted that we have been vaccinating children for many years.
For those who prefer the truth over mainstream propaganda, here are five things you really need to know about HPV vaccines:
1. Merck needed a new cash cow to replace the billions in profits lost due to Vioxx finally being pulled from the market after it caused upwards of 50,000 deaths. Gardasil was selected to become the new cash cow and, Continue reading →
High levels of the B vitamin folate (folic acid) may prevent heart birth defects induced by alcohol exposure in early pregnancy, a condition known as fetal alcohol syndrome.
Research on animals at the University Of South Florida College Of Medicine and All Children’s Hospital shows that folate taken early in pregnancy and before alcohol exposure could protect fetuses from these heart problems.
“Congenital heart defects can occur in the developing embryo at a time when women typically do not even know they are pregnant — 16 to 18 days following conception. They may have been drinking alcohol or Continue reading →
Numerous studies in recent months have tied agricultural pesticides to reproductive and other serious health problems (http://www.naturalnews.com/pesticid…). And a new study out of Argentina adds even more evidence to the fact that such chemicals are a widespread public health pandemic.
Andres Carrasco, head of the molecular Embryology Lab at the University of Buenos Aires, recently presented a report explaining that glyphosate, the active ingredient in Monsanto’s Roundup herbicide, is responsible for causing birth defects, infertility, sperm destruction, and cancer. Continue reading →
MIAMI – In a breakthrough study, a cell biologist at The Florida State University has found that the absence of a key molecular player, known as Pds5, could lead to a number of chromosomal birth defects like Down syndrome.
For the study, Hong-Guo Yu used yeast genetics and a novel scheme to selectively remove a single protein from the cell division process called meiosis.
He found that when a Pds5 goes missing, chromosomes fail to segregate and pair up properly, and birth defects such as Down syndrome can result.
The study sheds new light on the protein Pds5, its crucial regulatory role during meiosis, and the impact of its absence on the molecular-level genesis of human chromosomal birth defects that include Down, Edwards, Patau, Turner, Klinefelter’s and XYY syndromes.
The findings may contribute to the eventual development of targeted, molecular-level interventions.
Yu explained how the meiotic stage is set and what goes wrong when key elements are rearranged.
“To produce a genetically balanced gamete (sperm and egg), the cell must contend with two sets of chromosome pairs, homologs and sisters. Homologs are the nearly identical chromosomes inherited from each parent; sisters are exactly identical pairs that are produced like photocopies as part of normal cell division,” he said.
“During normal meiosis, the process of division that halves the number of chromosomes per cell, my colleagues and I discovered that Pds5 regulates the pairing and synapsis (joining together) of ‘mom and dad’ homologs. We also learned that Pds5 plays a vital role in the synaptonemal complex, a glue-like protein structure that homologs use to literally stick together as they pair up. In addition, we found that, although sister chromatids enter meiosis in very close proximity to one another, Pds5 acts to inhibit synapsis between them, a good thing because, then, meiotic conditions support the necessary pairing of homologs,” he added.
On the other hand, removing Pds5 during meiosis triggers a chromosomal catastrophe.
“In order to observe what happened when the Pds5 went missing from the process, we performed a ‘molecular genetics trick’ that had never been applied to this particular protein before, and it worked. We successfully engineered yeast cells that shut down Pds5 only during meiosis, but not when they were vegetative,” said Yu.
Thus, Pds5 was no longer present to regulate homolog organization and transmission in the meiotic yeast cells.
The synaptonemal complex, which normally would support the synapsis of homologs by creating a sticky bond along their entire length, failed to form.
And in the resulting meiotic malfunction, the identical sister chromosomes began to synapse instead.
“When Pds5 is removed and sister chromatids become synapsed as a result, the segregation and recombination of homologs essential for genetic diversity fails. This finding is highly important, because failure to generate a crossover between homologs leads to chromosome missegregation and can cause human chromosomal birth defects such as Down syndrome, which affects about one in 800 newborns in the United States,” said Yu.
The study has been published in the Journal of Cell Biology. (ANI)