Healing Power from Positive Energy

Positive energy represents an important, foundational principle for healing from any chronic illness including cancer. Emotions, “energies in motion,” powerfully influence the immune system and other bodily functions. For optimal health, you have to avoid negative energies like fear, anxiety, resentment, anger and guilt that, studies show, weaken your immune system. Negative feelings can slow healing and may feed cancer growth.

If you or a loved one is chronically ill in any form, especially with cancer, you must implement one or more modalities that create positive emotion. “Feeling good” can greatly enhance the healing process.

Energy enhancers: Continue reading

Telemedicine Health Blog Achieves 100,000 Page Views a Month

– May 20, 2011 – (Beverly Hills, CA) – There seems to be no question as to whether the American public has an interest in the emerging world of Telemedicine.  Just visit, E Patient Health Care dot Com.  With over 100,000 page views a month, this Top 20 Blog doles out plenty of information on health issues  Continue reading

The Promise of Telemedicine

PRESS RELEASE

FOR IMMEDIATE DISTRIBUTION

The Promise of Telemedicine

By:  Jacques von Speyer – Chairman – CEO, US Tele-Medicine

Technology and communication channels exist today in such capacities that basic medical care may be provided to virtually Eighty Percent of the world population. That is a fact.

Family Medicine and all of its attending disciplines is the foothold of public and societal health.  That too is a fact.

Tele-Family Medicine” is the ultimate promise of Telemedicine worldwide.

The Family Medicine practitioner enjoys the greatest impact on community wellness and effective prevention in all of health care.  These paramount discretions which when employed correctly saves lives, prevents illness, reduces costs and provides a management tool for the prodigious benefits found in continuation of care programs, on a mass basis.

These operational truths remain scalable from a small HMO population to a regional and national effort.

Telemedicine is the single rational modality for providing Mass E-Care to millions of families.  Specifically for the multi-millions living within remote, underserved, urban, and disenfranchised populations.

Most recent Telemedicine endeavors have centered upon condition specific efforts such as Tele-Dermatology, Tele-Wound, Tele-Psychiatry, Tele-Cardiac, etc.  Regrettably, very little effort, other than those of US Tele-Medicine, was invested to encompass basic, primary, and preventative care into new Telemedicine protocols and devices.

Current telehealth efforts mistakenly emulate today’s existing and failing healthcare model by focusing on Specialty Care.  The trend however must promote Mass E-Care and recognizing that holistic/primary Family Medicine is the veritable cornerstone for any nation or society seeking a healthy foundation.

RPM (Remote Patient Monitoring) services using telemetric devices in patient’s homes are now becoming more the accepted and the preferred mode of managing some chronic conditions.  These efforts are reporting excellent results with patient hospital readmission reduced, costly emergency room visits have decreased, and patients enjoy a measurable increase in wellness.

This is only the prologue.  Device manufacturers are better served to consider initiating Family Medicine and preventative protocols into their programming.  Most current RPM systems are robust enough to accommodate such indoctrination.

Of course, simply monitoring without the facility to access and initiate immediate medical intervention, limits the scope and effectiveness of the devices.  US Tele-Medicine does provide 24 hour per day MD oversight at our National Triage Center, assuring our patients of immediate response to their needs.

The goal for US Tele-Medicine, our staff, and Medical Advisory Board is to merge Telemedicine protocols and devices with Family Medicine measures.  New guidelines and strategies for incorporating Mass E-Care into the world of Family Medicine and basic care, which are so fundamental to the current and future general health of any population, are now in development.

Irrespective of politics, health care does need reform and new stratagems specifically when we consider increasing costs and while our birth rates have receded somewhat, we are living longer and incurring greater incidents of chronic diseases.  There is also the daunting reality that soon, we shall be incorporating over Thirty Million new people into our health care rolls.

It is incumbent upon all of us in Health Care to provide a direct and personal channel for access to primary, cohesive, and coordinated medical care.  We need to use monitoring devices and medical technologies linked to broadband, phone, cellular, or satellite systems, and deliver these services directly into the homes of families anywhere and almost everywhere.

US Tele-Medicine remains at the forefront in global health care telehealth advances, with its committed efforts to provide Mass E-Care and Family Medical care, using the latest in telemedicine technologies and applications.  We encourage and call upon medical device manufacturers and medical providers and join us,  by undertaking immediate steps within their areas of influence to shape the tenets of Family Medicine into their future technologies and modalities.  The need is evident.

The Promise of Telemedicine is the facility to provide Mass E-Care and will be fulfilled when a patient in the remote plains of the Dakotas, or on the banks of the Colorado River, can enjoy access to basic and primary medical care at the touch of a button.  Collectively, we can reach this level of service in the very near future, and ensure our population of the medical support required and desired through life.

www.ustelemedicine.com

Hay Fever Symptoms Reduced with Pycnogenol

You might ward off and reduce allergy and hay fever symptoms if you take a pine bark supplement known as Pycnogenol® several weeks before allergy season starts, according to a study published in Phytotherapy Research. Pycnogenol appears to reduce hay fever symptoms such as itchy eyes and nasal congestion.

About 60 million people in the United States experience symptoms of hay fever, also known as allergic rhinitis, according to the American Academy of Allergy Asthma and Immunology. Symptoms typically include inflamed nasal passages, sneezing, mucus production, rash, hives, itchy mouth, and itching, burning, watering eyes as well as facial pain and decreased sense of smell and taste.

The randomized, double-blind, placebo-controlled study was conducted by KGK Synergize, Inc., which recruited 60 individuals ages 18 to 65 who had all tested positive for birch pollen allergies. The participants began treatment three to eight weeks before onset of the birch allergy season in Ontario, Canada. Subjects were given instructions to take either one 50-mg Pycnogenol tablet or one placebo tablet twice daily throughout the allergy season (mid April to end of May). They were also allowed to take nonprescription antihistamines as needed, and they had to record use of these medications in treatment journals.

The participants were instructed to rate their nasal and eye symptoms each day using a questionnaire. All hay fever symptoms were rated on a scale ranging from zero (no symptoms) to three (severe symptoms completely prevented normal activities).

Throughout the entire allergy season, participants who took Pycnogenol scored lower on total average nasal and eye symptoms than those in the placebo group. A closer evaluation revealed that taking Pycnogenol was more effective the earlier the patients began taking it before allergy season started. The researchers speculated that for best results, individuals should begin taking Pycnogenol at least five weeks before pollen season starts.

In fact, only 12.5 percent of patients who began taking Pycnogenol seven weeks before the birch season began needed nonprescription antihistamines compared with 50 percent of patients who took placebo. Dr. Malkanthi Evans, scientific director of KGK Synergize Inc., noted that people with hay fever who want alternatives to medications that can cause side effects may find that Pycnogenol is “an effective and completely natural solution, void of any side-effects.”

Pycnogenol is an extract from the bark of the maritime pine tree that grows along the coast of southwest France. It contains a variety of phytochemicals, including procyanidins, bioflavonoids, and organic acids, which have been studied for their beneficial properties. Some studies have shown pycnogenol to be helpful in treating osteoarthritis, hemorrhoids, menopausal symptoms, and even attention deficit hyperactivity disorder.

In an earlier study, researchers at Loma Linda University compared the use of Pycnogenol with placebo in a group of 60 individuals who had mild to moderate asthma. Subjects who took Pycnogenol experience a significant improvement in pulmonary function and asthma symptoms when compared with the placebo group. Pycnogenol users were also able to reduce or stop their use of rescue inhalers more often than those in the placebo group.

Although hay fever symptoms may seem trivial to people who do not suffer with this allergic condition, Dr. Evans notes that “people suffering from hay fever may disagree as they experience a dramatic impairment to their quality of life.” Pycnogenol offers an effective, natural alternative to medications to treat symptoms of hay fever.

Researchers Solicit Cheap eHealth Alternative

Free software is secure, creators say

Researchers at Hamilton’s McMaster University say they have devised an electronic medical records system that can be implemented by physicians across Ontario for two per cent of the money the provincial government has spent on eHealth Ontario.

The web-based program, dubbed OSCAR, organizes medical records and can be set up on any computer system with a browser. It was first created in 2001, and has attracted more users each year.

Around 600 doctors across the country — including 450 family physicians in Ontario — currently use the software.

The software is open-source, which means users are allowed access to its basic code. Users are free to add to or modify the software without fear of legal repercussions, as long they abide by the conditions of the General Public Licence, which stipulates that the program must remain open and sharable.

Because it’s open-source, OSCAR is free. The costs to set it up come in the form of servers, hardware and support staff.

“In Ontario, there are approximately 8,000 family physicians that are not using electronic medical record systems. All these physicians could have OSCAR implemented within the next 24 months, and the cost would be less than $20 million,” Dr. David Price, chair of family medicine at McMaster’s medical school, said in a release.

While the software would be able to cover all the family physicians in Ontario, it is not as comprehensive in scope as eHealth, which is charged with linking all healthcare facilities, including hospitals and clinics, not just family doctors.

$1B spent already

Yet it can still help in digitizing Ontario’s medical records, said Dr. David Chan, who developed the software.

He said Ontario’s approach to building a health-record system is wrong. The province spent some $1 billion commissioning eHealth Ontario to produce an electronic medical database.

But in a report released Wednesday, Ontario Auditor General Jim McCarter said the province had wasted that investment and eHealth had little to show for its work.

We really don’t need to spend that kind of money. I think the government’s paranoia about building … a secure network is hugely expensive,” Chan said Friday.

People often get concerned about the security risks of open-source software, but Chan said it has passed stringent provincial security tests. It is no more vulnerable to hackers than more expensive proprietary software, he said.

Telemedicine Acknowledged by Medicare

American Medical News: Through teleconferencing technology, doctors are able to treat patients who live far away without access to a specialist. “Nationwide, telemedicine increasingly is being used to bridge gaps in access to care in rural and other medically underserved communities that have a hard time recruiting physicians. … The Centers for Medicare & Medicaid Services is making changes to promote telemedicine. In June, the agency proposed new policies that would make it easier for hospital officials to credential physicians who provide telemedicine services at their facilities. And in January 2011, CMS will expand Medicaid coverage for remote services, including disease management training for patients with diabetes or kidney disease” (Krupa, 11/22).

Austin American-Statesman: “Tech executives say Austin is positioned to be a player in health care technology, thanks to its deep pool of business software talent that is comfortable working in a startup environment and has expertise in creating products that save companies money. … So far, a handful of promising venture-backed players have emerged. … All in all, hundreds of computer hardware, software and services companies are competing for a piece of the market, which accelerated in 2009 with the passage of the federal economic stimulus bill, which set aside $19 billion in incentives for health care information technology. By one estimate, the government’s push to spur health care computer spending will help drive global health care IT spending to $106 billion by 2014, up from nearly $89 billion this year (Hawkins, 11/21).

The (Newark, N.J.) Star-Ledger: “Under federal health care reform, doctors must convert to an electronic system capable of chronicling each patient visit, tracking their care and sharing that information with hospitals and other doctors by 2015 — or the federal government will withhold some of the money it reimburses them for treating Medicare and Medicaid patients. … But so far, neither the promise of incentive nor threat of punishment is enticing a large number of New Jersey doctors to make the big switch. Only 20 percent of physicians in New Jersey have incorporated electronic medical records into their daily practice, compared to nearly 30 percent nationally, state Health and Senior Services Commissioner Poonam Alaigh said” (Livio, 11/21).

Telemedicine May Help Individuals with Type 2 Diabetes Improve their Diet

Type 2 diabetes requires significant amounts of dietary planning and continued consumption of healthy foods. However, due to the struggling economy, low wages and high unemployment, many individuals with the condition are finding it difficult to maintain a healthy diet and to stay in touch with their physicians.

A new study published in the Journal of Nutrition Education and Behavior has found that telemedicine, which allows patients to communicate with their doctors electronically, may help solve some of these problems.

Researchers from the State University of New York in Syracuse said that as many as 10 percent of adults with diabetes consider money to be a problem when it comes to sticking to a nutritious diet. However, after a round of counseling via telemedicine that covered less expensive ways they can stick to dietary recommendations, researchers found that a majority of participants improved their diets.

“This study demonstrated that among participants classified as both foods secure and mildly insecure, individuals were usually able to follow the dietitian’s advice,” said Ruth Weinstock, who led the investigation. “This finding suggests that telemedical nutrition support services have the potential to be an important adjunct for primary care providers whose patients have poor access to the services of dietitians.”

Omega Fish Oil Supplements are Vital for Life

Fish oil supplements contain essential fatty acids (lipids) that are particularly found in cold water fish. Omega 3 can also be obtained from other marine life like phytoplankton which is an excellent source of long-chain polyunsaturated fatty acids (LCPUFA) of the n-3 (omega-3) type.

The health benefits that come from omega 3 fatty acids are simply astounding – so much so that both conventional and alternative medicine agree, which is something that rarely occurs. High dosage of fish oil can improve a person’s physical performance, prevent heart disease, make someone smarter and thinner; helps reduce pain and inflammation, helps in reversing cancer as well as the aging process, and treating neurological diseases.

Omega 3 Fish oils may also be useful for those suffering from asthma, bipolar disorder, depression, heart attack and schizophrenia. It may also help with kidney, lupus, psoriasis, ulcerative colitis and Raynaud’s disease. Additionally, it may be useful for atherosclerosis, breast-feeding support, cardiac arrhythmia, cystic fibrosis, eczema, pre- and post-surgery health and sickle cell anemia.

Fish oil is also thought to be valuable to the immune function especially for seriously ill patients and those suffering post surgery. It may also be of use to those suffering from osteoporosis by combining it with evening primrose oil. It might also be helpful to those with phenylketonuria which occurs if the person is deficient in polyunsaturated fatty acids.

Fish oil supplement also contain the 20 carbon eicosapentaenoic acid (EPA) which is the key fat for health and the 22-carbon docosahexaenoic acid (DHA) which is the key fat for the brain. DHA helps build the neural tissue while the EPA helps alleviate constricted blood vessels, increase cell division, dilate blood vessels, enhance the immune system, improve brain function and reduce pain.

EPA also promotes cell division, moderate pain and blood clots so that a person does not to bleed to death. It also prevents Alzhemir’s disease, arthritis, cancer, chronic infection, depression, heart attack, hypertension and stroke.

Despite the numerous benefits that one can attain from omega 3 fatty acids, many health experts believe that it is one of the most important nutrients missing in a person’s diet. Researchers cite this as one of the reasons why there are so many who suffer from cancer, brain disorders and heart diseases.

It is no wonder there are numerous fish oil supplements that are now being marketed to help combat diseases and prevent ailments. One of the more popular brands of fish oil supplements would be Omega 1000EC which is endorsed by experts. Omega 1000EC is ultra high potency with 600mg EPA and 400mg DHA, it is enteric coated and is molecularly distilled to remove impurities. High doses of EPA and DHA found in Omega 3 fish oil supplements are believed to address health issues including   blood pressure, memory loss, bone density loss, burns, high cholesterol, colon cancer, depression, diabetes, eating disorders, heart disease, menstrual pain, skin problems, vision problems, weight loss and  attention deficit / hyperactivity disorder (ADHD). In short, fish oil supplements are believed to offer numerous health benefits for today’s most common health concerns.

Fish oil supplements contain essential fatty acids (lipids) that are particularly found in cold water fish. Omega 3 can also be obtained from other marine life like phytoplankton which is an excellent source of long-chain polyunsaturated fatty acids (LCPUFA) of the n-3 (omega-3) type.

The health benefits that come from omega 3 fatty acids are simply astounding – so much so that both conventional and alternative medicine agree, which is something that rarely occurs. High dosage of fish oil can improve a person’s physical performance, prevent heart disease, make someone smarter and thinner; helps reduce pain and inflammation, helps in reversing cancer as well as the aging process, and treating neurological diseases.

Omega 3 Fish oils may also be useful for those suffering from asthma, bipolar disorder, depression, heart attack and schizophrenia. It may also help with kidney, lupus, psoriasis, ulcerative colitis and Raynaud’s disease. Additionally, it may be useful for atherosclerosis, breast-feeding support, cardiac arrhythmia, cystic fibrosis, eczema, pre- and post-surgery health and sickle cell anemia.

Fish oil is also thought to be valuable to the immune function especially for seriously ill patients and those suffering post surgery. It may also be of use to those suffering from osteoporosis by combining it with evening primrose oil. It might also be helpful to those with phenylketonuria which occurs if the person is deficient in polyunsaturated fatty acids.

Fish oil supplement also contain the 20 carbon eicosapentaenoic acid (EPA) which is the key fat for health and the 22-carbon docosahexaenoic acid (DHA) which is the key fat for the brain.  DHA helps build the neural tissue while the EPA helps alleviate constricted blood vessels, increase cell division, dilate blood vessels, enhance the immune system, improve brain function and reduce pain.

EPA also promotes cell division, moderate pain and blood clots so that a person does not to bleed to death. It also prevents Alzheimer’s disease, arthritis, cancer, chronic infection, depression, heart attack, hypertension and stroke.

Despite the numerous benefits that one can attain from omega 3 fatty acids, many health experts believe that it is one of the most important nutrients missing in a person’s diet. Researchers cite this as one of the reasons why there are so many who suffer from cancer, brain disorders and heart diseases.

It is no wonder there are numerous fish oil supplements that are now being marketed to help combat diseases and prevent ailments. One of the more popular brands of fish oil supplements would be Omega 1000EC which is endorsed by experts. Omega 1000EC is ultra high potency with 600mg EPA and 400mg DHA, it is enteric coated and is molecularly distilled to remove impurities.

High doses of EPA and DHA found in Omega 3 fish oil supplements are believed to address health issues including   blood pressure, memory loss, bone density loss, burns, high cholesterol, colon cancer, depression, diabetes, eating disorders, heart disease, menstrual pain, skin problems, vision problems, weight loss and  attention deficit / hyperactivity disorder (ADHD). In short, fish oil supplements are believed to offer numerous health benefits for today’s most common health concerns.

Turn Off the Lights at Night to Lose Weight

WASHINGTON – It is well known that too much junk food and lack of exercise makes us fat. But a new research suggests there may be another factor at play: too much light at night.

The study in mice has shown that persistent exposure to light at night may lead to weight gain, even without changing physical activity or eating more food.

Researchers found that mice exposed to a relatively dim light at night over eight weeks had a body mass gain that was about 50 percent more than other mice that lived in a standard light-dark cycle.

“Although there were no differences in activity levels or daily consumption of food, the mice that lived with light at night were getting fatter than the others,” said Laura Fonken, lead author of the study and a doctoral student in neuroscience at Ohio State University.

The study appears this week in the online early edition of the Proceedings of the National Academy of Sciences.

Obesity’s Impact on Gastrointestinal Health

The association between obesity and gastrointestinal-related cancers and coronary artery disease; the link between an overweight or obese body mass index and the severity of Crohn’s disease; and whether inflammatory bowel disease is an independent risk factor for coronary artery disease, were among the highlights of new research that was presented this week at the American College of Gastroenterology’s (ACG) 75th Annual Scientific meeting in San Antonio.

Although liver cancer (hepatocellular carcinoma/HCC) in the absence of cirrhosis, fibrosis or hepatitis B is a rare occurrence, estimates show up to 10 percent of liver cancer occurs in non-cirrhotic livers.

“Previous studies have suggested that obesity and insulin resistance may be risk factors for non-cirrhotic hepatocellular carcinoma, prompting us to analyze data from a cohort of 12 patients with non-cirrhotic HCC who underwent partial hepatectomy between January 2008 and September 2009 at a single center,” said researcher Benjamin Mitlyng, M.D., a fellow with the University of Minnesota’s Division of Gastroenterology, Hepatology and Nutrition. “We evaluated preoperative data including age, gender, presence of liver disease, body mass index (BMI), number of lesions and other comorbidities; data related to the resection, such as background history, tumor size, and vascular invasion; as well as post-operative complications and mortality,” Dr. Mitlyng explained.

The study, “Hepatocellular Carcinoma in the Non-Cirrhotic Liver is Associated With a High Body-Mass Index Independent of Steatosis,” found that patients with non-cirrhotic HCC had a high prevalence of diabetes and elevated BMIs despite a lack of steatosis. However, even with advanced disease, patients tolerated resection very well with minimal complications, no operative mortality and average tumor-free follow-up of 17.5 months, according to the study.

“These findings support previous data that there may be an association with non-cirrhotic HCC and an elevated BMI as well as diabetes independent of steatosis,” said Dr. Mitlyng.

Body Mass Index was also linked with adenoma recurrence in the short-and long-term, in another study unveiled today, “The Association of Obesity with Short-and-Long-Term Risk of Adenoma Recurrence: Analysis of the Polyp Prevention Trial and Continued Follow-Up Study.”

“Previous prospective studies have evaluated the association between obesity and colorectal adenoma recurrence within four years of follow-up, a relatively short duration,” said Adeyinka Laiyemo, M.D. “We aimed to examine long-term cumulative risk of adenoma recurrence in association with obesity among participants in the Polyp Prevention Trial (PPT), a multicenter, randomized controlled trial that evaluated the effect of a low fat, high fiber, fruits and vegetable diet on the risk of colorectal adenoma recurrence,” explained Dr. Laiyemo.

The study, found that at baseline, approximately 50 percent of the 760 participants were overweight (BMI 25-29 kg/m2) and 25 percent were obese (BMI = 30 kg/m2). The mean age of participants was 59.7 years and 66 percent were males. The mean total duration of follow-up was 8.4 years (range 4.9 -12.4 years).

“When compared with participants with normal BMI, overweight and obese participants have an elevated risk of adenoma recurrence during both short-term and long-term,” said Dr. Laiyemo. “Since BMI was positively associated with adenoma recurrence in short-and-long-term, lifestyle modification should be encouraged.”

High Prevalence of Coronary Artery Disease in Patients with Non-Alcoholic Fatty Liver Disease

With Non-Alcoholic Fatty Liver Disease (NAFLD) affecting up to 20 percent of adults and nearly five percent of children, researchers aimed to assess the prevalence and predictors of coronary artery disease (CAD) in patients with NAFLD. NAFLD is a very common disorder and refers to a group of conditions where there is accumulation of excess fat in the liver of people who drink little or no alcohol. Both NAFLD and CAD are complications of metabolic syndrome.

A total of 93 patients who had a suspicion of CAD and were scheduled for cardiac catheterization were included in the study, “High Prevalence of Coronary Artery Disease (CAD) in Patients with Non-Alcoholic Fatty Liver Disease (NAFLD),” which found that among the 60 patients with available abdominal imaging, the prevalence of NAFLD was 30 percent.

“These patients who were found to have NAFLD were older, more commonly male, had higher weight and were also more commonly diabetic, hypertensive and had hyperlipidemia,” explained researcher Noreen Hossain, M.D., of the Center for Liver Diseases, Inova Fairfax Hospital, Fairfax, Va. “The prevalence of angiographically-proven coronary disease in the NAFLD cohort was 61 percent compared to 26 percent in the non-NAFLD controls,” said Dr. Hossain. “As a result, NAFLD is strongly associated with angiographically-proven CAD,” explained Dr. Hossain. “We found that diabetes is independently associated with both NAFLD and CAD.”

Is Inflammatory Bowel Disease A Risk Factor for Coronary Artery Disease?

The link between chronic bowel inflammation and coronary artery disease (CAD) was explored in another study, “Is Inflammatory Bowel Disease a Risk Factor for Coronary Artery Disease,” which focused on 79 patients who had confirmed inflammatory bowel disease (IBD) and CAD diagnosis. Forty-six patients had ulcerative colitis and 52 percent were males in the study group, compared to 40 percent males in the control group. Using the Framingham risk score FRS), which is calculated based on age, sex, hypertension, diabetes, tobacco use, total cholesterol and HDL values, the study found that FRS was lower in patients with IBD and CAD compared with the control group of patients with just CAD, implying that IBD is an independent risk factor for CAD.

“Recurrent flares of intestinal mucosal inflammation leads to the presence of excess pro-inflammatory cytokines and serum soluble adhesion molecules in IBD that could promote atherosclerosis-related inflammation, alter lipid metabolism, and contribute to plaque instability and rupture,” said researcher Tarun Rustagi, M.D., of the Department of Internal Medicine, University of Connecticut. “Our results are in accordance with those published by smaller studies.” Dr. Rustig also explained that further prospective cohort studies are needed to accurately investigate the incidence of CAD in patients with IBD.

In other findings, Crohn’s disease patients who are overweight or obese (BMI>25) are more likely to have more severe disease characterized by a higher likelihood of Vitamin D deficiency, stricturing ileocolonic disease, and are more likely to require surgery compared to normal weight patients (BMI < 24.9) with Crohn’s disease, according to the study, “The Clinical Phenotype of Obese and Overweight Crohn’s Disease Patients.”

Source: American College of Gastroenterology (ACG)

Palm Oil Derivative Shown To Be Effective In Lowering Fat Levels In Blood

Scientists from Singapore found that tocotrienols, which are members of the Vitamin E family, are effective in lowering the levels of triglyceride, a form of fat in the blood. High levels of triglyceride are closely linked to an increased risk of cardiovascular and metabolic diseases.

The scientists found that gamma and delta tocotrienols, derived naturally from palm oil, are potent in lowering triglyceride levels by 28% in the blood of human subjects after two months of supplementation. In addition, tocotrienol-treated subjects in the double blind, placebo-controlled human trial showed decreasing trends in average weight, body fat mass, body fat percentage and waist measurement. The study hence points to the potential of tocotrienols as a natural remedy in fighting obesity.

This research study, which involves collaboration between scientists at Davos Life Science (Singapore), researchers at Malaysia Palm Oil Board (Malaysia) and Phytopharma Co. Ltd. (Japan), was reported in the October 2010 issue of Journal of Atherosclerosis and Thrombosis, the reputable publication of the Japan Atherosclerosis Society. The study involved twenty human subjects with borderline hypercholesterolemia and was conducted in Takara Clinic in Japan. The subjects were not receiving any cholesterol-lowering medications at baseline.

“Other studies have shown triglyceride-lowering effects of eicosapentaenoic acid (EPA), a polyunsaturated fatty acid found in oily fish, which is approved by Japan’s Ministry of Health as a treatment for hyperlipidemia. This study reveals that tocotrienols have a more significant serum triglyceride-lowering effect than EPA.

More importantly, tocotrienol did not have any observable side effects, suggesting that it could become a natural remedy to lower triglycerides effectively,” said Dr. Daniel Yap, Head for Tocotrienol R&D, Davos Life Science.

An elevated triglyceride level is one of the risk factors for the identification of metabolic syndrome, which is linked to an increase risk of cardiovascular disease, diabetes and stroke. This study demonstrates – for the first time – that gamma and delta tocotrienols work to lower triglyceride levels, by directly suppressing genes that enable triglyceride production (SREBP1/2, DGAT2 and APOB100), suggesting that tocotrienols are able to directly regulate triglyceride synthesis in the body. At the same time, this down-regulation also translates into a reduction in the level of triglyceride transport lipoproteins (VLDL and chylomicron), which distribute fats around the body. The study supports its in vitro research findings, by demonstrating the triglyceride-lowering effect of tocotrienols in both mice models and human clinical studies.

Moreover, the study also showed that tocotrienols may inhibit the development of atherosclerosis, a medical condition in which fatty plaque, resulting from oxidation of LDL-cholesterol (also known as ‘bad’ cholesterol), builds up inside the arteries. It was found that gamma tocotrienol can enhance the removal of LDL-cholesterol from the blood, by inducing the expression of LDL receptors. This is a key step in achieving healthy blood lipid levels.

“Our studies show that tocotrienols have the potential for the prevention or treatment of metabolic syndrome. This research contributes further evidence that natural tocotrienols is a far more powerful form of vitamin E with unique healthrelated benefits not shared by alpha-tocopherol, the common form of vitamin E,” said Mr Arthur Ling, CEO of Davos Life Science Singapore, a company specialising in the research & development and production of tocotrienols.

Experts Decide Whether Parental Alienation is a Disorder

The American Psychiatric Association has a hot potato on its hands as it updates its catalog of mental disorders — whether to include parental alienation, a disputed term conveying how a child’s relationship with one estranged parent can be poisoned by the other.

There’s broad agreement that this sometimes occurs, usually triggered by a divorce and child-custody dispute. But there’s bitter debate over whether the phenomenon should be formally classified as a mental health syndrome — a question now before the psychiatric association as it prepares the first complete revision since 1994 of its Diagnostic and Statistical Manual of Mental Disorders.

“We’re gotten an enormous amount of mail — more than any other issue,” said Dr. Darrel Regier, vice chair of the task force drafting the manual. “The passions on both sides of this are exceptional.”

On one side of the debate, which has raged since the 1980s, are feminists, advocates for battered women and others who consider “parental alienation syndrome” to be an unproven and potentially dangerous concept useful to men trying to deflect attention from their abusive behavior.

“This is a fabricated notion — there’s no science to support it,” said Joan Meier, a professor at the George Washington University Law School who has written extensively on domestic violence and child custody.

On the other side are legions of firm believers in the existence of a syndrome, including hundreds gathering for a conference on the topic this weekend in New York. They say that recognition of parental alienation in the psychiatrists’ manual would lead to fairer outcomes in family courts and enable more children of divorce to get treatment so they could reconcile with an estranged parent.

“This is a problem that causes horrible outcomes for children. … All the arguments I’ve heard against it are trivial,” said Dr. William Bernet, a psychiatry professor at the Vanderbilt University School of Medicine.

Bernet is among the speakers at this weekend’s conference, which organizers bill as the largest ever on parental alienation. He will be describing his efforts as lead author of the proposal submitted to the psychiatric association to recognize parental alienation either as a “mental disorder” or a “relational problem.”

The psychiatric association first published its manual of diagnostic disorders, known as the DSM, in 1952. The last major revision was published in 1994 and updated in 2000, and the fifth edition — DSM-5 — is due for publication in May 2013.

Work groups in various fields have been reviewing numerous proposals for additions to the 283 disorders in the current edition. Parental alienation remains on a list of proposals that are subject to further review, though it did not pass muster with the work group dealing with childhood and adolescent disorders.

“There is not sufficient scientific evidence to warrant its inclusion in the DSM,” Regier said in a statement.

In an interview, Regier — who directs the APA’s research division — said the proposal technically remains alive pending final presentations by the end of 2011. But he described chances for inclusion of parental alienation as “slim” — given that it has not been selected for field trials that normally would be a prerequisite for official recognition.

Bernet said it was “flatly ridiculous” for the APA to contend there is not enough information available to warrant including parental alienation in the DSM. He cited legal developments and new research in numerous foreign countries.

His proposal defines parental alienation disorder as “a mental condition in which a child, usually one whose parents are engaged in a high conflict divorce, allies himself or herself strongly with one parent, and rejects a relationship with the other parent, without legitimate justification.”

The weekend conference at the Mount Sinai School of Medicine is the brainchild of Joseph Goldberg, who is based near Toronto and in 2008 founded an organization called the Canadian Symposium for Parental Alienation Syndrome.

Goldberg runs a consulting service for lawyers and parents litigating issues related to parental alienation. In his online biography, he says he “fought one of the most brutal case of parental alienation in Palm Beach County history” during a child-custody dispute with his ex-wife in Florida that extended from 2003 to 2006.

“This touches lives of more people than anyone imagines,” Goldberg said by telephone from Canada. “It’s not just about a child turned against a parent, through hatred. This affects grandparents, aunts and uncles, cousins, friends — all of them thrown out when a child rejects a parent.”

Some of Goldberg’s allies doubt the psychiatric association is ready to include parental alienation in its manual. New York-based psychologist Amy Baker, who has written a book about parental alienation, suggested the association might “play it safe” and decline to recognize it for fear of provoking feminist groups.

However, Goldberg is hopeful.

“There’s a long way to go over the next few years before they make a final decision,” he said. “There will be enormous pressure. …I think it will be difficult for the APA not to include it.”

Parental alienation surged onto the pop-culture radar screen a few years ago as a consequence of the bitter divorce and child custody battle involving actors Alec Baldwin and Kim Basinger. Baldwin was harshly criticized by some feminist groups for citing parental alienation syndrome as a source of his estrangement with his daughter.

The concept is a source of confusion and division in the legal profession, as some lawyers try to evoke parental alienation and others challenge that tactic.

Texas Supreme Court Justice Debra Lerhmann, chair of the American Bar Association’s family law section, said the issue of possible alienation can be raised in child custody proceedings whether or not any such phenomenon is classified as a disorder by health professionals.

“Anyone who’s in this business knows there are situations where that in fact is happening — and sometimes it’s alleged but is not happening,” she said. “Even if it’s not in the manual, relevant evidence can still be brought in.”

Meier, the George Washington law professor, has urged judges to be cautious in how they allow the topic to be raised in cases where one estranged parent is accused by the other of abuse.

“You’ve got to assess the abuse first, without poisoning it with a claim of alienation,” Meier said. “Only after abuse is ruled out do you then move on to the question of alienation.”

Elizabeth Kates, a Pompano Beach, Fla., lawyer who deals often with child custody cases, is skeptical of the role parental alienation can play in such disputes: “It’s a very easy claim to make … but the problem arises when it’s used in court to obscure the investigation of whether there’s been abuse.”

She said the initial impetus for recognition of parental alienation syndrome came in large part from the fathers’ rights movement, but suggested much of the momentum now comes from psychologists, consultants and others who could profit if the concept had a more formal status in family court disputes.

“It’s monetary,” Kates said. “These psychologists and therapists make huge money doing the evaluations and therapies.”

When You’re Depressed, the World Really Does Fade to Grey

When you are depressed, everything around you really does look grey, according to a team of German scientists who say that depression causes changes in vision.

Depression has an effect on the eyes that makes it harder to detect distinct black and white contrasts, with the result that everything fades into blandness.

The researchers carried out tests on the retinas of patients which showed the effect — similar to turning down the contrast control on a TV.

It could be one reason why throughout the ages and regardless of culture or language, artists have consistently depicted depression using symbols of darkness or grey uniformity.

The effect was so marked that scientists believe the test could provide an objective way of measuring depression levels.

The study, conducted by Dr Ludger Tebartz van Elst and researchers at the University of Freiburg, has been published in the journal Biological Psychiatry.

Dr John Krystal, who edits the journal, said: “These data highlight the profound ways that depression alters one’s experience of the world.

“The poet William Cowper said that ‘variety’s the very spice of life’, yet when people are depressed, they are less able to perceive contrasts in the visual world. This loss would seem to make the world a less pleasurable place,” he added.

The researchers measured electrical responses to gauge the activity of the retina in two groups of depressed and non-depressed individuals. The retina, at the back of the eye, contains the sensitive cells that turn light signals into nerve messages, making it possible to see.

Depressed patients were found to have dramatically lower retinal contrast “gain” than the volunteers who were not suffering from depression. It made no difference whether or not they were receiving antidepressant medication.

There was also a significant correlation between the level of contrast gain and symptom severity. Patients with the most depression had the lowest retinal responses. The pattern was so consistent it was possible to distinguish highly depressed patients from healthy volunteers simply by looking at the test results.

With further work, “electroretinogram” tests could provide a better way of assessing a patient’s mood than simply asking: “How do you feel?” the scientists believe.

Dr Tebartz van Elst said: “This method could turn out to be a valuable tool to objectively measure the subjective state of depression, having far-reaching implications for research as well as clinical diagnosis of and therapy for depression.”

Kids with ADHD More Likely to Have Missing DNA

Kids with ADHD More Likely to Have Missing DNA

Children with attention deficit hyperactivity disorder are twice as likely to have missing or extra chromosomes than other children — the first evidence that the disorder is genetic, a new study says.

British researchers compared the genomes of 366 white British children from 5 to 17 years old with attention deficit hyperactivity, or ADHD, to those of more than 1,000 similar children without the disorder. The scientists focused on a sequence of genes linked to brain development that has previously been connected to conditions like autism and schizophrenia.

In children without ADHD, about 7 percent of them had deleted or doubled chromosomes in the analyzed gene sequence. But among children with the disorder, researchers discovered about 14 percent had such genetic alterations. Scientists also found that 36 percent of children with learning disabilities in the study had the chromosomal abnormalities.

“This is the first time we’ve found that children with ADHD have chunks of DNA that are either duplicated or missing,” said Anita Thapar, a professor at the MRC Centre in Neuropsychiatric Genetics and Genomics at Cardiff University who was one of the study’s authors.

She said the findings are too early to affect diagnosis or treatment and are only applicable to people of European Caucasian descent because studies have not been done yet on other ethnicities.

The condition is estimated to affect millions of children around the world, and scientists have long thought the disorder has a genetic component.

U.S. experts estimate that ADHD affects from three to five percent of school-age children in the United States. There are no figures for developing nations.

The study was paid for by Action Research, Baily Thomas Charitable Trust, the Wellcome Trust, Britain’s Medical Research Council and the European Union. It was published online Wednesday in the medical journal Lancet.

Peter Burbach, a professor of molecular neuroscience at University Medical Center Utrecht in the Netherlands, was surprised some of the genetic defects found for ADHD were identical to ones for autism and schizophrenia. He was not connected to the Lancet research.

“There’s a great chance the environment is modifying these genes,” Burbach said, adding the genes could lead to several brain disorders, depending on things like the child’s upbringing and other genetic factors.

He also thought scientists might eventually be able to reverse ADHD.

“This is not a structural abnormality in the brain, it’s just the last phase of development that’s gone wrong,” he said. “It could be the brain just needs to be fine-tuned.”

Philip Asherson, a professor of molecular psychiatry at the Institute of Psychiatry at King’s College London, said the study only dealt with a subset of people with ADHD and said the environment should still be considered a cause. In the case of some Romanian orphans, Asherson said there was proof that severe deprivation at an early age can lead to ADHD or other neurological problems.

Asherson said the medical world was still years away from being able to correct ADHD.

“The study doesn’t tell us a lot about what’s going on in the brains of people with ADHD,” he said. “If we can find out more about these genes and how they affect brain development, that may give us inroads, but it’s hard to say when that will be.”

High Cholesterol in Young People Hurts Them in Middle Age

Take note, kids. What you do to your body today really could hurt you a few decades from now.

A new study that followed more than 3,000 young adults into middle age found that people who had high cholesterol in their 20s were much more likely to show early signs of atherosclerosis in their 40s than those who had “optimal” cholesterol levels.

That may seem kind of obvious — after all, anyone who has high cholesterol in his 20s is likely to have high cholesterol in his 40s and 50s, too. What’s compelling, researchers say, is that the study suggests that the people may actually be doing irreversible harm in their youth.

“You have to start thinking about cholesterol levels early in life, because what you do early in life matters later on. You can’t put these things off until later,” said Dr. Mark Pletcher, an epidemiologist and biostatistician at the University of California at San Francisco who was the lead author of the study. The study was published in Monday’s edition of the Annals of Internal Medicine.

It has long been assumed, at least by young adults, that whatever damage they do to their bodies in their 20s can be magically erased, or at least mostly undone, by improving their health in their 30s and 40s.

But the new study, which included research out of the San Francisco campus and Kaiser Permanente in Oakland, Calif., suggests that the harm done by high cholesterol starts early and builds over time. Young people may not realize they’re causing long-term damage and setting themselves up for heart disease later in life, researchers say.

The results are particularly compelling now, as several recent studies have found that most Americans in their 20s — and many teenagers, too — have high cholesterol. In fact, in the new study, more than 75 percent of participants had high cholesterol in their 20s and 30s, and only 13 percent maintained optimal cholesterol levels through their young adulthood.

Yet most in their 20s have no idea whether their cholesterol is high, doctors say. National guidelines recommend that everyone have their cholesterol checked at age 20, but many young adults don’t see their doctors for regular checkups and don’t go out of their way to get tested for heart disease indicators like cholesterol or blood pressure.

“Young folks don’t necessarily come to the doctor very often, and they’re not focused on preventing problems two or three decades later,” said Dr. Anthony Steimle, chief of cardiology at Kaiser Permanente in Santa Clara, Calif., who was not involved with the study. “The good news is it’s never too late to modify your lifestyle. But you probably can’t completely undo the effects of a decade or two of bad lifestyle. It’s best to begin (a good lifestyle) at a very young age.”

The new research came from a national study that has followed 3,258 people over 25 years to assess their risk of heart disease over time. The participants were ages 18 to 30 when they joined the study in 1985. They come from four U.S. cities — Kaiser Oakland is one of the participating centers.

The cholesterol research was based on follow-up exams with participants in 2005. The research looked at participants’ average cholesterol levels between ages 20 and 35, their cholesterol level at the follow-up exam, and the amount of coronary calcium in their arteries, which is a strong predictor of future heart disease.

Of the 434 participants who maintained optimal cholesterol levels through age 35, only 8 percent had coronary calcium in theirs 40s. For the 2,443 participants who had high cholesterol, 44 percent had coronary calcium.

The fact that high cholesterol at a relatively young age was connected to later coronary calcium — whether or not individuals had high cholesterol later in life — was a “missing link” in research into heart disease risk and age, Pletcher said.

“Before our study, you could have made the argument that it’s very clear that your cholesterol level right now predicts your heart disease tomorrow,” Pletcher said. “This study links exposure during young adulthood with damage that lasts into middle age.”

Whether young adults should be put on cholesterol-lowering medications is a question worth pursuing, researchers said. The drugs might improve long-term risk of heart disease, but it is not clear if there are health hazards associated with decades of exposure to such drugs.

But the results suggest that at the very least, young adults should find out their cholesterol levels and, if necessary, try to lower those levels through diet and exercise, doctors and researchers said.

“It’s important to look at yourself when you’re a young person, because heart disease is really a lifelong disease,” said Dr.

Steve Sidney, associate director for clinical research at Kaiser Northern California, who was one of the study authors. “It can start in childhood. But it doesn’t manifest itself in heart attack or stroke until decades later.”