More vindication for a natural Mediterranean-style diet, including plenty of extra virgin olive oil (EVOO) and nuts was revealed in an advanced study published by the prestigious journal Atherosclerosis. Early results from a Spanish study with more than 7500 participants demonstrates that high quantities of dietary EVOO and a variety of different species of nuts is more effective in managing and preventing a heart event than traditional drug therapy. Many physicians place their patients on the standard prescription of beta blockers and ACE inhibitors in a desperate effort to prevent advancing heart disease, even though repeated studies prove these drugs are detrimental to long-term health. Include copious amounts of EVOO and nuts in your diet to dramatically lower heart disease risk and avoid the need for risk drugs. Continue reading
EVANSTON – A naturally-occurring compound found in extra-virgin olive oil can help prevent and treat Alzheimer’s disease, say researchers.
The team from Monell and Northwestern researchers has found that the compound called oleocanthal alters the structure of neurotoxic proteins believed to contribute to the debilitating effects of Alzheimer’s.
This structural change impedes the proteins’ ability to damage brain nerve cells.
“The findings may help identify effective preventative measures and lead to improved therapeutics in the fight against Alzheimer’s disease,” said study co-leader Dr Paul A.S. Breslin, a sensory psychobiologist at the Monell Center.
Known as ADDLs, these highly toxic proteins bind within the neural synapses of the brains of Alzheimer’s patients and are believed to directly disrupt nerve cell function, eventually leading to memory loss, cell death, and global disruption of brain function.
Synapses are specialized junctions that allow one nerve cell to send information another.
“Oleocanthal alters ADDL structure in a way that deters their binding to synapses,” said
Knowing that oleocanthal changed ADDL size, the researchers next examined whether oleocanthal affected the ability of ADDLs to bind to synapses of cultured hippocampal neurons.
The hippocampus, a part of the brain intimately involved in learning and memory, is one of the first areas affected by Alzheimer’s disease.
Measuring ADDL binding with and without oleocanthal, they discovered that small amounts of oleocanthal effectively reduced binding of ADDLs to hippocampal synapses.
Additional studies revealed that oleocanthal could protect synapses from structural damage caused by ADDLs.
The findings are reported in the journal Toxicology and Applied Pharmacology.