Measles Vaccine Inhaler Shows Promise

Posted on by

DENVER – Scientists from University of Colorado have revealed that inhaling measles vaccine can be more effective in combating the disease that causes 197,000 deaths each year globally.

While a liquid vaccine using a hypodermic needle is presently the only way to prevent the disease, they are often difficult to store, costly to transport and may be prone to contamination when shipped to developing countries.

The study led by Dr Robert Sievers shows promise for a new method that allows the patient to inhale a finely-powdered medicine.

In order to produce the inhalant, the weakened measles virus must be mixed with high-pressure carbon dioxide to produce microscopic bubbles and droplets, which are then gently dried to produce an inhalable powder.

The powder is then puffed into a small inhaler-like device and administered.

The aerosol vaccine was shown effective in test animals, and human trials are expected to begin next year in India, where more than half of the world’s measles cases occur.

Aridis Pharmaceuticals have been working to develop a room temperature stable measles formulation that can be easily inhaled using cost-effective dry-powder inhalers in collaboration with the non-profit foundation PATH.

“There is a need for technologies that could stabilize the measles vaccine, as this would facilitate mass vaccination in developing world countries where transport, storage, administration costs and other complexities have limited vaccine coverage by 70 percent,” said Dr Satoshi Ohtake, from Aridis and the study’s principal investigator.

Ohtake’s study used a combination of mild spray drying process conditions and unique stabilizers to produce stable dry powders with excellent preservation of vaccine activity.

The potency of the dried vaccine was then tested while being stored at different Temperatures over several week-long periods.

The results found that the dry-powdered aerosol was stable for at least eight weeks at 37 degrees Celsius.

“This new method could potentially offer safer, more affordable and effective treatments to patients that need them the most,” Ohtake added.

86 thoughts on “Measles Vaccine Inhaler Shows Promise”

  2. You actually make it appear so easy along with your presentation however I to find this matter to be actually
    something which I believe I would never understand.
    It sort of feels too complex and very large for me. I’m having a look ahead to your subsequent submit,
    I will try to get the hang of it!

  3. Today, while I was at work, my sister stole my iPad and
    tested to see if it can survive a thirty foot drop, just so she can be a youtube sensation. My
    iPad is now broken and she has 83 views. I know this is totally off topic but I had to share it with someone!

  15. Hello There. I found your blog the use of msn. That is a very well
    written article. I will make sure to bookmark it and come back to
    read more of your useful info. Thanks for the post. I will definitely return.

  16. Pingback: These '80s-inspired leggings are fan favorites for their comfort – Lil Diamonds Baseball

  17. Heya tһis is kind of of off topic but I wɑs wanting to know if blogs use WҮSIᎳYԌ editors or if you һave to manually code with HTML.
    I’m starting a bⅼog soⲟn Ƅut have no coding experience so I wanted to
    get guidance from someone with experience. Any help ԝould be
    greatly appreciated!

  18. The other day, while I was at work, my cousin stole my iphone and tested to
    see if it can survive a thirty foot drop, just so she can be
    a youtube sensation. My iPad is now destroyed and she has 83 views.
    I know this is completely off topic but I had to share it with someone!

  20. Yes most modern evening associations can be found today thanks to online dating sites internet websites.
    All internet websites supply good expert services and excellent final results worldwide.

    Thus, you will have numerous probabilities for you to arrange hookup internet dating or older courting with
    regional men and women or associates worldwide.
    Essential Tips in order that the Success of Your Over 40 Dating, below
    are the issues that you need to contemplate when you are evaluating your prospected night out on-line.
    And Grow Naughty offers the sophisticated functions that could be actually
    effective to its customers to make best use of if they are in search of prospective companions
    to start out a conversation that can result in be nothing day in real life.
    Subscribe and initiate without having put in Bonus 1000 loose change.
    Whatever you are expecting which has a benaughty app, it’ll spare with
    out to generate every little thing straightforward for you, like mischievous adult dating,
    casual courting, friendships, fwb relationships, adult
    chat, etcetera. This will likely come to be one of your ideal connection wordpress that you’d like to help keep
    with your phone for many years due to the fact it may help you’re making new good friends and
    begin no matter what form of dating that you’d like in a while.

  25. Hey there! This post could not be written any better!
    Reading through this post reminds me of my good old
    room mate! He always kept chatting about this. I will forward this article
    to him. Pretty sure he will have a good read.
    Many thanks for sharing!

  26. Excellent write up, I need to truly enhance the
    content I have.
    I have attemptedto blog on third part platforms,
    it just did
    not transpire the true way I wanted it to. However your
    website has
    giving me a desire to do so. I will be bookmarking
    your website
    and checking it out every once in awhile. Many thanks!

  28. I must thank you for the efforts you have put in penning this site.

    I’m hoping to see the same high-grade blog posts from you later on as well.
    In fact, your creative writing abilities has encouraged me to get my very own site now 😉

  29. Every weekend і used to go to see thіs web page, because i wiѕh for enjoyment, for the reason that this this web site cօnations genuinely nice funny material too.

    my web-site :: gov-india

  30. Wow, amazing blog format! How long have you been blogging for?

    you make blogging glance easy. The whole look of your website is excellent,
    let alone the content material!

  31. Wonderful blog! I found it while browsing on Yahoo News.

    Do you have any tips on how to get listed in Yahoo News?
    I’ve been trying for a while but I never seem to get there!

    Cheers

  35. When I originally left a comment I appear to have clicked
    the -Notify me when new comments are added- checkbox and from now on every time a
    comment is added I get four emails with the exact same comment.
    There has to be a way you are able to remove me from that service?
    Many thanks!

  37. Hi are using WordPress for your site platform?
    I’m new to the blog world but I’m trying to get started and create my own.
    Do you require any html coding expertise to make your own blog?
    Any help would be really appreciated!

  42. I think this is one of the most significant information for me.
    And i am glad reading your article. But should remark on some general things, The site
    style is ideal, the articles is really nice : D. Good job, cheers

  47. สมัครเล่น หวย ออนไลน์ผ่านเว็บไซต์ตรงมีหวยให้เล่นมากมายกว่า 20 แบบ ไม่ว่าจะเป็น หวยรัฐบาล หวยฮานอย
    หวยยี่กี หวยมาเลย์ หวยหุ้น ทั้งไทย และ ต่างประเทศ หวยโจ๊กเกอร์ เปิดให้แทงกันได้ตลอด 24 ชั่วโมง
    รับแทงไม่อั้น แทงหวยออนไลน์ รับแทงไม่อั้นไม่มีขั้นต่ำในการแทง
    หวยออนไลน์

  51. Everyone loves what you guys tend to be up too. This type of clever
    work and reporting! Keep up the superb works guys I’ve included you
    guys to my personal blogroll.

  52. I’m not that much of a online reader to be honest but your blogs really nice, keep it up!
    I’ll go ahead and bookmark your website to come back later on. Cheers

  54. After I originally left a comment I seem to have clicked the -Notify
    me when new comments are added- checkbox and now each time a
    comment is added I receive four emails with the same comment.
    Is there an easy method you can remove me
    from that service? Many thanks!

  55. Have you ever considered about including a little bit more than just your articles?
    I mean, what you say is fundamental and all.
    Nevertheless imagine if you added some great visuals or video clips to give your posts more,
    “pop”! Your content is excellent but with pics and video clips,
    this blog could definitely be one of the most beneficial in its field.
    Great blog!

  57. I loved as much as you will receive carried out right here.
    The sketch is attractive, your authored material stylish. nonetheless, you command get got an edginess over that you
    wish be delivering the following. unwell unquestionably come more
    formerly again since exactly the same nearly very often inside case
    you shield this hike.

  58. I’ve been browsing on-line more than 3 hours nowadays, but I never discovered any fascinating article
    like yours. It’s lovely value enough for me. Personally,
    if all website owners and bloggers made good content material as
    you did, the internet shall be a lot more helpful than ever before.

  59. Everything is very open with a precise description of
    the challenges. It was definitely informative. Your website is very helpful.
    Thanks for sharing!

  60. Have you ever considered about including a little bit more than just your articles?
    I mean, what you say is valuable and all. But just imagine if
    you added some great photos or videos to give your posts more,
    “pop”! Your content is excellent but with images and videos, this site could undeniably be one of the best in its field.

    Very good blog!

  61. Its such as you read my mind! You seem to understand so much about this, such as you wrote
    the guide in it or something. I think that you just can do with
    a few p.c. to pressure the message house a little bit, however other than that,
    this is excellent blog. An excellent read.
    I’ll definitely be back.

  63. Wonderful beat ! I would like to apprentice while you amend your website, how can i
    subscribe for a blog site? The account aided me a acceptable
    deal. I had been a little bit acquainted of this your broadcast offered bright
    clear concept

  66. naturally like your website but you have to take a look at the spelling on quite a few of your posts.
    Several of them are rife with spelling issues and
    I to find it very troublesome to inform the reality nevertheless I’ll certainly come
    back again.

  69. Terrific article! That is the type of information that should be shared across the internet.
    Shame on Google for now not positioning this submit higher!
    Come on over and consult with my website .
    Thanks =)

  70. My partner and I stumbled over here different page and thought I might as well check
    things out. I like what I see so i am just following you.
    Look forward to finding out about your web page repeatedly.

  71. Hello there, I found your site by means of Google while searching for a comparable subject, your
    web site got here up, it seems to be great.
    I have bookmarked it in my google bookmarks.

    Hi there, simply became aware of your weblog through Google, and located that it’s truly informative.
    I’m gonna watch out for brussels. I will appreciate
    if you continue this in future. Many people will be benefited
    out of your writing. Cheers!

  73. I am really inspired together with your writing skills as neatly as with the layout on your
    blog. Is this a paid topic or did you modify it yourself?
    Anyway stay up the excellent high quality writing, it’s uncommon to see a nice blog like this one today..

  75. With havin so much written content do you ever
    run into any issues of plagorism or copyright infringement?
    My website has a lot of exclusive content I’ve either written myself or outsourced but it seems a lot of it is popping it up all over
    the internet without my permission. Do you know any methods to help prevent
    content from being stolen? I’d definitely appreciate it.

  76. Thanks for any other excellent article. The place else may just anybody
    get that type of information in such a perfect way of writing?
    I’ve a presentation next week, and I’m at the look for such
    information.

  78. Woah! I’m really loving the template/theme of this website.
    It’s simple, yet effective. A lot of times it’s hard
    to get that “perfect balance” between user friendliness and
    appearance. I must say you’ve done a fantastic job
    with this. Also, the blog loads super quick for me on Safari.
    Exceptional Blog!

  79. Thanks for the marvelous posting! I seriously enjoyed
    reading it, you are a great author. I will make sure to bookmark your blog and
    will come back later on. I want to encourage one to continue
    your great job, have a nice morning!

  80. Thank you a lot for sharing this with all folks you
    really recognize what you are talking about! Bookmarked.

    Please also consult with my site =). We will have a hyperlink change contract
    between us

  83. Attractive section of content. I just stumbled upon your weblog and in accession capital to assert that I get in fact
    enjoyed account your blog posts. Any way I’ll be subscribing to your augment and even I
    achievement you access consistently fast.

  85. At last, I found this post once again. You have few [url=http://tipswift.com]useful tips[/url] for my school project. Now, I won’t forget to bookmark it. 🙂

Leave a Reply

Your email address will not be published. Required fields are marked *