Thyroid Hormone Controls Visual Pigment in Cones

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What part does the thyroid gland have in vision? Thyroid hormone is crucially involved in controlling which visual pigment is produced in the cones. Previously, it was assumed that the color sensitivity of the cones is fixed in the adult retina. Researchers at the Max Planck Institute for Brain Research in Frankfurt/M., together with colleagues at the University of Frankfurt and universities in Vienna, have now been able to show that in mature cones of mice and rats the production of visual pigment is regulated by thyroid hormone. It is assumed that this mechanism exists in all mammals, including humans. If so, the adult-onset of thyroid hormone deficiency would affect color vision.

Thyroid hormone has a crucial role during development of the body and also of the nervous system. Children born with a thyroid hormone deficiency have serious defects of physiological and mental development, hence newborns are routinely checked for thyroid Continue reading