The other day my friend Nell woke up and complained of a sharp pain behind her eye. She said it felt as if she was being stabbed with an ice pick. Continue reading
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An estimated 300,000 Americans are diagnosed with Lyme disease each year, and the prevalence is rising across the US, even in states that have not reported any cases of Lyme before Continue reading
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A low-fat diet and statin medication is a recipe for chronic health problems, as both strategies actually promote cardiovascular problems
2011 guidelines for Continue reading
Eating peppers – but not other vegetables in the Solanaceae family — was associated with a 19 percent lower risk of Parkinson’s disease in a new study
The association was strongest among those who Continue reading
Exercise is a foundational strategy to naturally maintain healthy cholesterol levels and optimize your heart health. However, research now shows that if you take a statin drug, you’re likely to forfeit any and all health benefits of your exercise
Volunteers taking a statin improved their fitness by just 1.5 percent, Continue reading
• The U.S. Food and Drug Administration (FDA) is requiring additional warning labels for the cholesterol-lowering drug class known as statins, warning that the drugs may increase your risk of liver damage, memory loss and confusion, type 2 diabetes and muscle weakness
• The FDA has removed Continue reading
Often prescribed to alleviate symptoms of illness, pharmaceutical medications rarely attack the root cause and cure the illness and have the added downside of side-effects.
Aside from the litany of side-effects listed, new book “Drug Muggers: Which Medications Are Robbing Your Body of Essential Nutrients” suggests the medications may be further adding to your state of illness by “stealing nutrients from your system or preventing their absorption.” Not only might this make you feel worse, but it also may cause you to develop another condition.
Author of the new book, leading U.S. pharmacist Suzy Cohen, claims, “If you run low on even one vital nutrient, you can experience a cascade of uncomfortable side effects,” Continue reading
Omega-3 deficiency is the sixth biggest killer of Americans, according to a new study.
Harvard University researchers looked at 12 dietary, lifestyle and metabolic risk factors such as tobacco smoking and high blood pressure, and used a mathematical model to determine how many fatalities could have been prevented if better practices had been observed.
The study determined that there were 72,000-96,000 preventable deaths each year due to omega-3 deficiency, highlighting the importance of establishing a dietary reference intake (DRI) for omega-3 forms such as EPA (eicosapentaenoic acid) and DHA (docosahexaenoic acid).
Another study found that a combination of omega-3 fatty acids and coenzyme Q10 (CoQ10) decreased blood pressure and heart rate in kidney disease patients.
People with chronic kidney disease (CKD), which increases the risk of heart disease, experienced improvements in both blood pressure and heart rate following supplementation with four grams of omega-3 fats.
Furthermore, when the omega 3’s were taken in combination with coenzyme Q10, the blood pressure reducing benefits were enhanced. CKD is linked to increased prevalence in all-cause mortality, cardiovascular events and hospitalization.
In addition to benefitting your physical health, omega-3 fats can also be good for your mind.
Researchers have shown that depressed patients have, on average, lower levels of omega-3 in their blood than nondepressed individuals. A greater severity of depression is also linked to lower levels of omega-3. A number of well-controlled depression treatment studies have found therapeutic benefits following omega-3 supplementation.
Other Names: Coenzyme Q10, Co Q10, Ubiquinone, Vitamin Q
CoQ10 is a naturally-occuring compound found in every cell in the body. CoQ10’s alternate name, ubiquinone, comes from the word ubiquitous, which means “found everywhere.”
CoQ10 plays a key role in producing energy in the mitochondria, the part of a cell responsible for the production of energy in the form of ATP.
Why People Use CoQ10
- Heart failure
- Heart Attack Prevention and Recovery
- High Blood Pressure
- Gum Disease
- Kidney Failure
- Counteract Prescription Drug Effects
- Parkinson’s disease
- Weight loss
What is the Evidence For CoQ10?
- Heart failure
People with heart failure have been found to have lower levels of CoQ10 in heart muscle cells. Double-blind research suggests that CoQ10 may reduce symptoms related to heart failure, such as shortness of breath, difficulty sleeping, and swelling. CoQ10 is thought to increase energy production in the heart muscle, increasing the strength of the pumping action. Recent human studies, however, haven’t supported this.
In one study, 641 people with congestive heart failure were randomized to receive either CoQ10 (2 mg per kg body weight) or a placebo plus standard treatment. People who took the CoQ10 had a significant reduction in symptom severity and fewer hospitalizations.
In another study, 32 patients with end-stage heart failure awaiting heart transplantation received either 60 mg of CoQ10 or a placebo for 3 months. Patients who took the CoQ10 experienced a significant improvement in functional status, clinical symptoms, and quality of life, however there were no changes in echocardiogram (heart ultrasound) or in objective markers.
A study randomized 55 patients with congestive heart failure to receive either 200 mg per day of CoQ10 or a placebo in addition to standard treatment. Although serum levels of CoQ10 increased in patients receiving CoQ10, CoQ10 didn’t affect ejection fraction, peak oxygen consumption, or exercise duration.
A longer-term study investigated the use of 100 mg of CoQ10 or a placebo in addition to standard treatment in 79 patients with stable chronic congestive heart failure. The results indicated that CoQ10 only slightly improved maximal exercise capacity and quality of life compared with the placebo.
Several small trials have found CoQ10 may be helpful for certain types of cardiomyopathy.
- Parkinson’s disease
Lower levels of CoQ10 have also been observed in people with Parkinson’s disease. Preliminary research has found that increasing CoQ10 may increase levels of the neurotransmitter dopamine, which is thought to be lowered in people with Parkinson’s disease. It has also been suggested that CoQ10 might protect brain cells from damage by free radicals.
A small, randomized controlled trial examined the use of 360 mg CoQ10 or a placebo in 28 treated and stable Parkinson’s disease patients. After 4 weeks, CoQ10 provided a mild but significant significant mild improvement in early
A larger 16 month trial funded by the National Institutes of Health explored the use of CoQ10 (300, 600 or 1200 mg/day) or a placebo in 80 patients with early stage Parkinson’s disease. The results suggested that CoQ10, especially at the 1200 mg per day dose, had a significant reduction in disability compared to those who took a placebo.
- CoQ10 and Statin Drugs
Some research suggests that statin drugs, or HMG-CoA reductase inhibitors, a class of drugs used to lower cholesterol, may interfere with the body’s production of CoQ10. However, research on the use of CoQ10 supplements in people taking statins is still inconclusive, and it is not routinely recommended in combination with statin therapy.
In a 12-week randomized controlled trial, 74 people with type 2 diabetes were randomized to receive either 100 mg CoQ10 twice daily, 200 mg per day of fenofibrate (a lipid regulating drug), both or neither for 12 weeks. CoQ10 supplementation significantly improved blood pressure and glycemic control. However, two studies found that CoQ10 supplementation failed to find any effect on glycemic control.
- Gum disease
A small study looked at the topical application of CoQ10 to the periodontal pocket. Ten male periodontitis patients with 30 periodontal pockets were selected. During the first 3 weeks, the patients applied topical CoQ10. There was significant improvement in symptoms.
A typical CoQ10 dosage is 30 to 90 mg per day, taken in divided doses, but the recommended amount can be as high as 200 mg per day.
CoQ10 is fat-soluble, so it is better absorbed when taken with a meal that contains oil or fat.
The clinical effect is not immediate and may take up to eight weeks.
Consult your doctor before trying CoQ10, especially if you have heart disease, kidney failure, or cancer.
Side effects of CoQ10 may include diarrhea and rash.
CoQ10 is used in combination with standard treatment, not to replace it.
CoQ10 may lower blood sugar levels, so people with diabetes should not use CoQ10 unless under a doctor’s supervision. CoQ10 may also lower blood pressure.
The safety of Co q10 in pregnant or nursing women or children has not been established.
PLEASE SEE THE POST ON “POLICOSANOL” FOR LOWERING CHOLESTEROL