Why Narcoleptics Get Fat

People with narcolepsy are not only excessively sleepy, but they are also prone to gaining weight. In fact, narcoleptic patients will often pack on pounds even as they eat considerably less than your average person.

Now researchers reporting in the October issue of Cell Metabolism, a Cell Press publication, appear to have an answer as to why. It seems a deficiency of the neuropeptide hormone orexin, an ingredient that encourages hunger and wakefulness, may leave them with a lack of energy-burning brown fat.

The findings may lead to orexin-based weight loss therapies for those with narcolepsy Continue reading