How Safe Are the Nanoparticles in Moderna’s Vaccine?

STORY AT-A-GLANCE

  • Moderna and Pfizer’s COVID-19 vaccines use lipid nanoparticles that contain polyethylene glycol (PEG) to deliver mRNA to your cells
  • This experimental mRNA technology and its lipid nanoparticle-based delivery system have never been approved for use in a vaccine or drug
  • Significant concerns have been raised over the technology, including the lipid nanoparticles, and Moderna actually abandoned it in 2017 after studies revealed a high rate of adverse effects
  • Experts have questioned whether LNPs are safe, as research shows they readily enter the brain and may trigger immune reactions
  • The first dose of COVID-19 vaccine may prime the body to have an immune reaction to LNPs, such that when the second dose is received, a stronger likelihood for adverse events exists
  • The PEG found in both Pfizer’s and Moderna’s vaccines could also be causing allergic reactions and anaphylaxis 

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