Melatonin — A Standard Treatment Adjunct for COVID-19?

STORY AT-A-GLANCE

  • Recent research suggests melatonin may be an important adjunct to COVID-19 treatment
  • Patients hospitalized with COVID-19 pneumonia who were given high-dose melatonin as an adjunct therapy to standard of care improved within four to five days, and all survived
  • Melatonin inhibits the cytokine storm associated with critical SARS-CoV-2 infection. It also inhibits sepsis (blood poisoning), associated with an overactive immune response
  • Melatonin helps prevent mitochondrial impairment, energy failure and apoptosis (programmed cell death) in mitochondria damaged by oxidation
  • Melatonin also helps regulate and improve risk factors for severe COVID-19, such as high blood pressure, insulin resistance and diabetes

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The Importance of Melatonin for Optimal Health

STORY AT-A-GLANCE

  • Your circadian rhythm is largely dictated by your pineal gland, located near the center of your brain, which produces melatonin, a hormone that is crucial for the regulation of your sleep cycle
  • Melatonin is also an important energy hormone and a potent antioxidant that appears to play an important role in cancer prevention. It also benefits your brain, cardiovascular and gastrointestinal health, and has been shown to boost immune function
  • Melatonin helps protect your mitochondria, which generate energy inside your cells. Melatonin appears to be the most powerful antioxidant in this regard, as it has the ability to enter into your mitochondria. It also recharges glutathione
  • Melatonin works synergistically with vitamin D to optimize mitochondrial function. It also enhances vitamin D signaling
  • Multiple sclerosis, cancer, neuropsychiatric disorders and high blood pressure are all examples of diseases that appear strongly linked to and affected by your vitamin D and melatonin status

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