Grape and Grape Extract Compounds Protect Against Alzheimer Progression

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Researchers publishing the result of a study in the Journal of Alzheimer`s Disease found that eating grapes and supplementing with grape seed extract compounds help to prevent the development and progression of Alzheimer`s dementia. This devastating form of dementia is characterized by the accumulation of beta-protein clusters in the brain known as oligomers. A wealth of prior research studies concludes that excess oligomers poison neurons in the brain and cause memory loss associated with the disease. A number of different natural compounds, including grapes and grape extracts, provide a powerful protective shield against the progressive memory loss experienced with Alzheimer`s dementia.

Researchers wanted to follow up on prior studies showing that grape seed polyphenolic extract (GSPE) stops alpha-beta oligomers from being formed in test tube experiments. Using mice that have been bred to genetically develop Alzheimer`s disease, scientists set to determine the effect of grape polyphenols on cognitive decline. For a period of five months they added GSPE to a standard diet and tested the mice for signs of memory deterioration normally found in this line of transgenic animals.

After the five month period, researchers found that the mice had dramatically lowered levels of alpha beta-56, Continue reading