Ovarian cancer is one of the most deadly diseases out there. It is the fifth leading cause of cancer death among U.S. women — an astounding 14,000 out of 23,000 diagnosed each year, die. Ovarian cancer tends to be aggressive and generally has very few symptoms until it reaches an advanced stage. Fortunately, several natural remedies have proven to be exceptionally useful in both preventing and curing this silent killer. Ginger, ginkgo biloba, green tea and flaxseed are all remarkably effective Continue reading
Proteomics reveals how ancient remedy slows prostate tumor cell proliferation
An over-the-counter natural remedy derived from honeybee hives arrests the growth of prostate cancer cells and tumors in mice, according to a new paper from researchers at the University of Chicago Medicine.
Caffeic acid phenethyl ester, or CAPE, is a compound isolated from honeybee hive propolis, the resin used by bees to patch up holes in hives. Propolis has been used for centuries as a natural remedy Continue reading
Numerous studies have established melatonin as one of the most effective anti-cancer treatments in existence. It inhibits cancer cell growth and proliferation; it destroys cancer cells, stops angiogenesis (new tumor blood vessel growth), and prevents harmful forms of estrogen from stimulating cancer cell growth. Despite its success in clinical trials and in doctors’ experiences with their patients, it has not been widely prescribed in conventional medicine, though its effects have proven to be superior to those of many chemotherapeutic drugs.
In one clinical trial, patients with glioblastoma, a type of brain cancer, were given either radiation and melatonin, or radiation alone. Twenty-three percent of the patients who took the melatonin were alive after a year, while none who had received only radiation were still alive. Similarly, in another study by oncologists in Italy, patients with non-small cell lung cancers who had failed chemotherapy were given melatonin. They were compared with other patients with non-small cell lung cancers who weren’t given melatonin. A year later, 26 percent of the patients who had taken melatonin were still alive; Continue reading
Cell communication is essential for the development of any organism. Scientists know that cells have the power to “talk” to one another, sending signals through their membranes in order to “discuss” what kind of cell they will ultimately become — whether a neuron or a hair, bone, or muscle. And because cells continuously multiply, it’s easy to imagine a cacophony of communication.
But according to Dr. David Sprinzak, a new faculty recruit of Tel Aviv University’s Department of Biochemistry and Molecular Biology at the George S. Wise Faculty of Life Sciences, cells know when to transmit signals — and they know when it’s time to shut up and let other cells do the talking. In collaboration with a team of researchers at the California Institute of Technology, Dr. Sprinzak has discovered the mechanism that allows cells to switch from sender to receiver mode or vice versa, inhibiting their own signals while allowing them to receive information from other cells — controlling their development like a well-run business meeting.
Dr. Sprinzak’s breakthrough Continue reading
Jerusalem scientists identify molecular basis for DNA breakage, which results in the development of cancer.
The molecular basis for the breakage of DNA – the hallmark of cancer cells – has been identified by Hebrew University of Jerusalem scientists. The important discovery will be published on Friday in the prestigious journal Molecular Cell.
The DNA encodes all the genetic information needed to build the cell’s proteins. Thus, breaks in the DNA disrupt the proteins and lead to changes in cell function. These changes can lead to defects in the control of cellular proliferation, which results in the development of cancer.
Using cutting-edge technologies, researchers Prof. Batsheva Kerem and doctoral student Efrat Ozeri-Galai, of the Alexander Silverman Institute of Life Sciences in the HU’s Faculty of Science, were able to characterize for the first time the DNA regions that are the most sensitive to breakage in early stages of cancer development.
This is a breakthrough in our understanding of the effect of the DNA sequence and structure on its replication and stability, they said on Thursday. Continue reading