A STAR Scientist Discovers how to Combat Hospital-Acquired Infections, Deadly Food Poisoning and Bioterrorism Toxins

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This study paves the way for developing toxin antidotes to safeguard public health and national security.

A team of scientists from A*STAR’s Institute of Molecular and Cell Biology (IMCB) has discovered the secret recipe for ‘antidotes’ that could neutralize the deadly plant toxin Ricin, widely feared for its bioterrorism potential, as well as the Pseudomonas exotoxin (PE) responsible for the tens of thousands of hospital-acquired infections in immune-compromised patients all over the world. The results of this first ever genome-wide study to understand how the Ricin and PE toxins attack cells may also be useful for designing more effective antidotes against Diphtheria and Shiga-like toxins secreted by infectious strains of E. coli bacteria, such as those responsible for the recent food poisoning Continue reading