Why You Don’t Want to Take Aspirin or Motrin for COVID-19


  • The French health ministry is warning against using nonsteroidal anti-inflammatories (NSAIDs) such as ibuprofen to treat fever and pain associated with COVID-19 infection, and to use acetaminophen (paracetamol) instead
  • There’s also an entirely different reason for avoiding NSAIDs and other antipyretics when you have a fever. Fever is part of your body’s immune response; it’s how your body kills pathogens
  • Treating fever can prolong and exacerbate illness, and has been shown to increase mortality
  • Research has also shown ibuprofen does not improve survival in patients with sepsis. Heat-shock proteins induced by fever protect against oxidative injury caused by sepsis, so by suppressing heat-shock proteins, antipyretic drugs have the potential to worsen outcomes


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