STORY AT-A-GLANCE
- Two scientifically demonstrated benefits of fasting are the suppression of mammalian target of rapamycin (mTOR) and the activation of autophagy, both of which play a role in disease prevention and longevity
- After the age of 30, extrapolations from animal studies suggest the longer you’re able to incorporate some form of regular fasting across your life span, the better
- When added to a low-calorie diet and healthy lifestyle, NAD boosters such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) appear to have a magnifying effect, allowing you to maximize your benefits
- Sirtuins are proteins that act as environmental stress sensors and are responsible for longevity. Activating sirtuins is one way to increase longevity in yeast and worms. One compound found to activate sirtuins is NAD. Another is resveratrol
- Research led by David Sinclair, Ph.D., has demonstrated it’s possible to reprogram cells, restoring their original youthfulness, and in so doing, reversing blindness by rejuvenating the nerves in the retina